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Merck

60229

Potassium phosphate monobasic

tested according to Ph. Eur., anhydrous

Synonym(s):

Kalii dihydrogenophosphas, Potassium dihydrogen phosphate, prim.-Potassium phosphate

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About This Item

Linear Formula:
KH2PO4
CAS Number:
7778-77-0
Molecular Weight:
136.09
NACRES:
NA.25
PubChem Substance ID:
329758833
UNSPSC Code:
12161700
EC Number:
231-913-4
MDL number:
MFCD00011401

Key Documents

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InChI key

GNSKLFRGEWLPPA-UHFFFAOYSA-M

InChI

1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1

SMILES string

[K+].OP(O)([O-])=O

grade

anhydrous

Quality Level

200

agency

tested according to Ph. Eur.

assay

98-100.5% dry basis

form

crystalline

loss

<2.0% loss on drying

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

mp

252.6 °C (lit.)

solubility

water: 208 g/L at 20 °C

density

2.338 g/mL at 25 °C (lit.)

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Application

Potassium phosphate monobasic buffer has been used as a component of the mobile phase in high-performance liquid chromatography (HPLC).

Biochem/physiol Actions

Potassium phosphate monobasic (MKP) is a commonly used buffering agent in biochemical and biological applications. It is used as a component of the buffer system in electrophoresis for the separation of biomolecules.

Features and Benefits

Assured high quality as it is tested according to both USP/NF and Ph. Eur. standards

General description

Potassium phosphate monobasic (KH2PO4), also known as monopotassium phosphate(MKP), is a soluble salt. It serves as a source of phosphorus and potassium. KH2PO4 is an essential component of potassium phosphate buffer, which is utilized in aqueous two-phase systems (ATPS) that are often used in the purification of lipases.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7091
BCCN5954
BCCM4476
BCCM0575
BCCM0152

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Vibrational spectroscopic studies (FTIR) of KDP, pure and doped with NH4Cl
Sheeba B, et al.
The Malaysian Journal of Analytical Sciences, 1255-1257 (2020)
Effect of buffer, electric field, and separation time on detection of aptamer-ligand complexes for affinity probe capillary electrophoresis
Buchanan DD, et al.
Electrophoresis, 24(9), 1375-1382 (2003)
In vitro studies: inhibition of nevirapine metabolism by nortriptyline in hepatic microsomes
Iris U and Esteban PJ
Bio-protocol, 5(19), e1607-e1607 (2015)
Novel aqueous two-phase systems based on tetrahydrofuran and potassium phosphate buffer for purification of lipase
L Ranyere S, et al.
Process Biochemistry (Oxford, United Kingdom), 50(9), 1459-1467 (2015)
LC method for the determination of oxcarbazepine in pharmaceutical preparations
Qi ML, et al.
Journal of Pharmaceutical and Biomedical Analysis, 31(1), 57-62 (2003)
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