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Merck

861340

Thionin acetate salt

certified by the BSC, Dye content ≥85 %

Synonym(s):

3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet

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About This Item

Empirical Formula (Hill Notation):
C12H9N3S · C2H4O2
CAS Number:
78338-22-4
Molecular Weight:
287.34
PubChem Substance ID:
24888537
UNSPSC Code:
12171500
NACRES:
NA.47
MDL number:
MFCD00081194
Colour Index Number:
52000
Beilstein/REAXYS Number:
4345073

Key Documents

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Product Name

Thionin acetate salt, certified by the BSC, Dye content ≥85 %

SMILES string

CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1

InChI

1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1

InChI key

OWXBIRAFHWASMS-UHFFFAOYSA-M

agency

certified by the BSC

form

powder

composition

Dye content, ≥85%

technique(s)

microbe id | staining: suitable

λmax

598 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Application

Thionin is widely used as a biological stain, especially in histology. It has been used in the Nissl stain for the labeling of neuronal cell bodies.

General description

Thionin is a diaminothiazine, metachromatic cationic dye.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT4046
SHBT4045
SHBR2794
SHBN8564
MKCM9285

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Resuscitation, 83, 1511-1511 (2012)
Contribution of carbohydrate histochemistry to glycobiology.
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Histology and Histopathology, 9, 155-155 (1994)
Yunying Xie et al.
Analytica chimica acta, 699(1), 44-48 (2011-06-28)
We reported a graphene-based immunosensor for electrochemical quantification of phosphorylated p53 on serine 15 (phospho-p53(15)), a potential biomarker of gamma-radiation exposure. The principle is based on sandwich immunoassay and the resulting immunocomplex is formed among phospho-p53 capture antibody, phospho-p53(15) antigen
Selvaraj Baskar et al.
Biosensors & bioelectronics, 33(1), 95-99 (2012-01-24)
We report here a novel detection scheme for simultaneous detection of NADH and H(2)O(2) based on a bifunctional poly(thionine)-modified electrode. Electropolymerization of thionine on a "preanodized" screen-printed carbon electrode effectively lowers the oxidation potential of NADH to 0.15 V (vs.
Aline Dall'Oglio et al.
The Journal of comparative neurology, 521(3), 589-611 (2012-07-19)
The medial nucleus (Me) is a superficial component of the amygdaloid complex. Here we assessed the density and morphology of the neurons and glial cells, the glial fibrillary acidic protein (GFAP) immunoreactivity, and the ultrastructure of the synaptic sites in
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