36799
7-(Diethylamino)coumarin-3-carboxylic acid
BioReagent, suitable for fluorescence, ≥98.0% (HPCE)
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About This Item
Empirical Formula (Hill Notation):
C14H15NO4
CAS Number:
Molecular Weight:
261.27
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6145963
InChI
1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)
SMILES string
CCN(CC)c1ccc2C=C(C(O)=O)C(=O)Oc2c1
InChI key
WHCPTFFIERCDSB-UHFFFAOYSA-N
product line
BioReagent
assay
≥98.0% (HPCE)
mp
222-224 °C (dec.) (lit.)
solubility
DMF: soluble, DMSO: soluble
fluorescence
λex 409 nm; λem 473 nm in 0.1 M Tris pH 9.0
suitability
suitable for fluorescence
Quality Level
Application
7-(Diethylamino)coumarin-3-carboxylic acid (7-DCCA) may be used to study its photophysical properties in various solvents and solvent mixtures and as a fluorescent label for amine modification and protein conjugation
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Fluorescent label for amine modification and protein conjugation
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Ilaria Catusi et al.
International journal of molecular sciences, 21(22) (2020-11-15)
Maternal uniparental disomy of chromosome 7 is present in 5-10% of patients with Silver-Russell syndrome (SRS), and duplication of 7p including GRB10 (Growth Factor Receptor-Bound Protein 10), an imprinted gene that affects pre-and postnatal growth retardation, has been associated with
Alicia S Kriete et al.
Interface focus, 9(4), 20190013-20190013 (2019-07-03)
Urinary incontinence is a significant challenge for women who are affected by it. We propose augmenting the tissue structure to restore normal biomechanics by molecularly engineering the tissue using a novel family of biomimetic proteoglycans (BPGs). This work examines the
Simone Kunzelmann et al.
Biochemistry, 49(5), 843-852 (2009-12-24)
A single-stranded DNA binding protein (SSB), labeled with a fluorophore, interacts with single-stranded DNA (ssDNA), giving a 6-fold increase in fluorescence. The labeled protein is the adduct of the G26C mutant of the homotetrameric SSB from Escherichia coli and a
Aninda Chatterjee et al.
Photochemistry and photobiology, 89(2), 280-293 (2012-09-26)
The photophysical properties of 7-(diethylamino) coumarin-3-carboxylic acid (7-DCCA) were studied in cyclodextrins (α, β, γ,-CDs), different neat solvents and solvent mixtures by using steady state absorption, emission and time-resolved fluorescence spectroscopy. We have observed that with gradual increase in concentration
Keisuke Ikeda et al.
Biochemical and biophysical research communications, 370(3), 525-529 (2008-04-09)
Amyloid beta-protein (Abeta) has been reported to interact with a variety of lipid species, although the thermodynamic driving force remains unclear. We investigated the binding of Abetas labeled with the dye diethylaminocoumarin (DAC-Abetas) to lipid bilayers under various conditions. DAC-Abeta-(1-40)
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