Skip to Content
Merck

B4153

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride

~95%

Synonym(s):

Boc-Gln-Ala-Arg-AMC hydrochloride, Boc-Gln-Ala-Arg-Mca hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C29H42N8O8 · HCl
CAS Number:
113866-20-9
Molecular Weight:
667.15
NACRES:
NA.32
PubChem Substance ID:
24891756
UNSPSC Code:
12352204
MDL number:
MFCD00080216

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

~95%

Quality Level

200

form

powder

solubility

methanol: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(NC(=O)C(CCC(N)=O)NC(=O)OC(C)(C)C)C(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C29H42N8O8/c1-15-13-23(39)44-21-14-17(8-9-18(15)21)35-26(42)19(7-6-12-33-27(31)32)36-24(40)16(2)34-25(41)20(10-11-22(30)38)37-28(43)45-29(3,4)5/h8-9,13-14,16,19-20H,6-7,10-12H2,1-5H3,(H2,30,38)(H,34,41)(H,35,42)(H,36,40)(H,37,43)(H4,31,32,33)

InChI key

LQSLBVXESNRILG-UHFFFAOYSA-N

General description

Substrate for trypsin
Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride is a fluorogenic and cell-permeable trypsin substrate.

Application

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride has been used as a fluorogenic substrate to measure the enzymatic activity of trypsin.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN9760
BCCK2636
BCBX5563
BCBP5435V
BCBK4691V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Evaluation of fluorogenic substrates in the assessment of digestive enzymes in a decapod crustacean Maja brachydactyla larvae
Rotllant G, et al.
Aquaculture (Amsterdam, Netherlands), 282(1-4), 90-96 (2008)
Morphological and physiological changes of Octopus bimaculoides: from embryo to juvenile
Ibarra-Garcia LE, et al.
Aquaculture (Amsterdam, Netherlands), 497, 364-372 (2018)
Diel food intake and digestive enzyme production patterns in Solea senegalensis larvae
Navarro-Guillen C, et al.
Aquaculture (Amsterdam, Netherlands), 435, 33-42 (2015)
Digestive biochemistry as indicator of the nutritional status during early development of the long snouted seahorse (Hippocampus reidi)
Novelli B, et al.
Aquaculture (Amsterdam, Netherlands), 464, 196-204 (2016)
Sudarshan R Malla et al.
Cellular and molecular life sciences : CMLS, 77(9), 1811-1825 (2019-08-01)
Premature intrapancreatic trypsinogen activation is widely regarded as an initiating event for acute pancreatitis. Previous studies have alternatively implicated secretory vesicles, endosomes, lysosomes, or autophagosomes/autophagolysosomes as the primary site of trypsinogen activation, from which a cell-damaging proteolytic cascade originates. To
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service