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Merck

G7387

Gly-His-Lys acetate salt

BioXtra, γ-irradiated, suitable for cell culture

Synonym(s):

Liver cell growth factor

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About This Item

Linear Formula:
C14H24N6O4C2H4O2
CAS Number:
72957-37-0
Molecular Weight:
400.43
MDL number:
MFCD00012699
UNSPSC Code:
12352209
PubChem Substance ID:
24895305
NACRES:
NA.77

Key Documents

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Product Name

Gly-His-Lys acetate salt, BioXtra, γ-irradiated, suitable for cell culture

Quality Level

200

SMILES string

CC(O)=O.NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(O)=O

InChI

1S/C14H24N6O4.C2H4O2/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);1H3,(H,3,4)/t10-,11-;/m0./s1

InChI key

MGNUTAFMLGJBGV-ACMTZBLWSA-N

biological source

synthetic (organic)

sterility

γ-irradiated

product line

BioXtra

form

powder

mol wt

400.43 g/mol

packaging

pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

impurities

<2 EU/mL

color

white

solubility

H2O: soluble 0.5 mg/mL, clear, colorless

storage temp.

−20°C

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Application

Gly-His-Lys acetate salt has been used:
  • as a component of the serum-containing medium to culture human thyroid cells
  • as a supplement to culture fisher rat thyroid cells
  • as a component of the Dulbecco′s modified Eagle Medium (DMEM)/HamF12/mesenchymal stem cell media to culture mesenchymal stem cells

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000449664
0000449664
0000395911
0000388525
0000387194

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Lars Kayser et al.
Acta histochemica, 107(1), 31-41 (2005-05-04)
The objective was to investigate glucose-6-phosphate dehydrogenase (G6PD) activity in monolayer cultures of thyroid epithelial cells and to examine whether inhibition of nitric oxide synthase affects activity of G6PD or oxygen sensitivity of the assay. Primary cultures without TSH addition
Hosny Salama et al.
Stem cell research & therapy, 5(3), 70-70 (2014-06-03)
We have assessed the utility of autologous mesenchymal stem cell (MSC) peripheral vein infusion as a possible therapeutic modality for patients with end-stage liver diseases. Forty patients with post-hepatitis C virus (HCV) end-stage liver disease were randomized into two groups:
Lars Kayser et al.
Acta histochemica, 107(1), 31-41 (2005-05-04)
The objective was to investigate glucose-6-phosphate dehydrogenase (G6PD) activity in monolayer cultures of thyroid epithelial cells and to examine whether inhibition of nitric oxide synthase affects activity of G6PD or oxygen sensitivity of the assay. Primary cultures without TSH addition
A Siméon et al.
The Journal of investigative dermatology, 115(6), 962-968 (2000-12-20)
Glycyl-histidyl-lysine-Cu(2+) is a tripeptide-copper complex previously shown to be an activator of wound healing. We have investigated the effects of glycyl-histidyl-lysine-Cu(2+) on the synthesis of glycosaminoglycans and small proteoglycans in a model of rat experimental wounds and in rat dermal
Christelle Hureau et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(36), 10151-10160 (2011-07-23)
The Gly-His-Lys (GHK) peptide and the Asp-Ala-His-Lys (DAHK) sequences are naturally occurring high-affinity copper(II) chelators found in the blood plasma and are hence of biological interest. A structural study of the copper complexes of these peptides was conducted in the
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