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Merck

N3002

Bis(p-nitrophenyl) phosphate sodium salt

chromogenic, ≥99% (TLC), powder

Synonym(s):

BNPP sodium salt, Sodium bis(4-nitrophenyl) phosphate

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About This Item

Linear Formula:
C12H8O8N2PNa
CAS Number:
Molecular Weight:
362.16
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
223-739-2
MDL number:
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Product Name

Bis(p-nitrophenyl) phosphate sodium salt, ≥99% (TLC)

Quality Level

assay

≥99% (TLC)

form

powder

impurities

≤0.05% free p-nitrophenol

solubility

water: 20 mg/mL, clear to very slightly hazy

storage temp.

−20°C

SMILES string

[Na].OP(=O)(Oc1ccc(cc1)N(=O)=O)Oc2ccc(cc2)N(=O)=O

InChI

1S/C12H9N2O8P.Na.H/c15-13(16)9-1-5-11(6-2-9)21-23(19,20)22-12-7-3-10(4-8-12)14(17)18;;/h1-8H,(H,19,20);;

InChI key

NXXNKMXTNUUECE-UHFFFAOYSA-N

Related Categories

General description

Phosphodiesterase substrate

Application

Bis(p-nitrophenyl) phosphate sodium salt has been used as a substrate for the estimation of phosphodiesterase (PDE) activity. It has also been used as a substrate in PDE inhibition assay.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Soper AS and Aird SD
Journal of Chromatography A, 1154(1-2), 308-318 (2007)
6-Nitrobenzimidazole derivatives: Potential phosphodiesterase inhibitors: Synthesis and structure-activity relationship
Khan KM, et al.
Bioorganic & Medicinal Chemistry, 20(4), 1521-1526 (2012)
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Julien Robert-Paganin et al.
PloS one, 7(12), e52424-e52424 (2013-01-04)
FimX is a large multidomain protein containing an EAL domain and involved in twitching motility in Pseudomonas aeruginosa. We present here two crystallographic structures of the EAL domain of FimX (residues 438-686): one of the apo form and the other

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