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Merck

AV35098

Anti-KCNN4 antibody produced in rabbit

affinity isolated antibody

Sinónimos:

Anti-IK1, Anti-IKCA1, Anti-KCA4, Anti-KCa3.1, Anti-SK4, Anti-Small conductance calcium-activated channel, subfamily N, member 4, Anti-hIKCa1, Anti-hKCa4

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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
28
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

mol wt

48 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNN4(3783)

General description

Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, KCNN4, is a component of a potassium channel activated by calcium. It is critically involved in calcium ion transport and cell homeostasis.

Immunogen

Synthetic peptide directed towards the C terminal region of human KCNN4

Application

Anti-KCNN4 antibody produced in rabbit has been used in:
  • western blot analysis
  • immunofluorescence
  • staining
  • immunohistochemistry

Biochem/physiol Actions

KCNN4 (potassium calcium-activated channel subfamily N member 4) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: DLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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