702153
Hydroxyapatite
nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)
Synonym(s):
Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
Molecular Weight:
502.31
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Form:
dispersion, nanoparticles
Quality Level
form
dispersion, nanoparticles
contains
≤0.025 wt. % dispersant (non-metal based)
concentration
10 wt. % in H2O
surface area
14.3 m2/g , typical
particle size
<200 nm (BET)
pH
4-6
density
1.038 g/mL at 25 °C
SMILES string
[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
InChI
1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10
InChI key
XYJRXVWERLGGKC-UHFFFAOYSA-D
General description
Hydroxyapatite(HAP) is an osteoconductive bioceramic material which has uniqueability to form direct bonds with living tissues. It can be easily prepared byvarious techniques such as sol-gel, hydrothermal, multiple emulsion, biomimeticdeposition, and electrodeposition.
Application
Hydroxyapatite can be used as:
- An implant material for bone substitute due to its chemical similarity to the inorganic component of bone and osteo inductive properties.
- A vehicle for gene and drug delivery because of its encapsulation capacity and affinity to several drugs and proteins.
- A pH responsive particulate emulsifier.
Features and Benefits
- Biocompatible
- Osteoconductive
- Stable under physiological conditions
- High mechanical strength
Legal Information
Product of Engi-Mat Co.
Still not finding the right product?
Explore all of our products under Hydroxyapatite
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Martin P Reichhardt et al.
Life science alliance, 3(4) (2020-02-27)
The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial
Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
Ehud Segal et al.
PloS one, 4(4), e5233-e5233 (2009-04-22)
There is an immense clinical need for novel therapeutics for the treatment of angiogenesis-dependent calcified neoplasms such as osteosarcomas and bone metastases. We developed a new therapeutic strategy to target bone metastases and calcified neoplasms using combined polymer-bound angiogenesis inhibitors.