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Merck

A65182

2-Amino-2-methyl-1-propanol

~5% Water, technical grade, 95%

Synonym(s):

β-Aminoisobutyl alcohol, AMP

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About This Item

Linear Formula:
(CH3)2C(NH2)CH2OH
CAS Number:
124-68-5
Molecular Weight:
89.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24891100
MDL number:
MFCD00008051
Beilstein/REAXYS Number:
505979
Assay:
95%
Form:
liquid

Key Documents

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grade

technical grade

Quality Level

200

vapor density

3 (vs air)

vapor pressure

<1 mmHg ( 25 °C)

assay

95%

form

liquid

impurities

≤5% 2-(Methylamino)-2-methyl-1-propanol, ~5% Water

refractive index

n20/D 1.4455 (lit.)

useful pH range

9.0-10.5

pKa (25 °C)

9.7

bp

165 °C (lit.)

mp

24-28 °C (lit.)

density

0.934 g/mL at 25 °C (lit.)

SMILES string

CC(C)(N)CO

InChI

1S/C4H11NO/c1-4(2,5)3-6/h6H,3,5H2,1-2H3

InChI key

CBTVGIZVANVGBH-UHFFFAOYSA-N

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Application

Used in an efficient synthesis of 2-oxazolidinones via carbonylation with CO in the presence of salen-cobalt catalysts.
Used to derivatize carboxylic acids for GC analysis and to synthesize 2-oxazolines for further transformations.

pictograms

Corrosion
GHS05

signalword

Danger

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

179.8 °F - closed cup

flash_point_c

82.1 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MKDB3884
SDBB7807
MKDB4269
MKCZ9735
MKCZ5875

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Journal of the American Chemical Society, 114, 1010-1010 (1992)
Journal of Chromatography A, 673, 101-101 (1994)
Erik C B Johnson et al.
Tetrahedron letters, 48(10), 1795-1799 (2007-03-05)
Modification of a peptide-(α)thioester with a sequence of six arginines on the thioester leaving group can render soluble all peptides derived from a polytopic integral membrane protein. This strategy greatly simplifies the synthesis of peptide-(α)thioester building blocks for the total
Tetrahedron, 49, 9353-9353 (1993)
Shia-Chung Chen et al.
Journal of hazardous materials, 179(1-3), 692-700 (2010-04-15)
In this study, the recovery of carbon dioxide using an absorbent composed of 2-amino-2-methyl-l-propanol (AMP)+monoethanolamine (MEA)+piperazine (PZ) in polytetrafluoroethylene (PTFE) membrane contactors was investigated. Experiments were conducted using various gas flow rates, liquid flow rates, absorbent blends, and pore size
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