M81101
mono-Methyl hydrogen succinate
95%
Synonym(s):
Monomethyl succinate, Succinic acid monomethyl ester
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About This Item
Linear Formula:
CH3OCOCH2CH2COOH
CAS Number:
Molecular Weight:
132.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
223-408-2
Beilstein/REAXYS Number:
1722669
MDL number:
Assay:
95%
Form:
powder
Quality Level
assay
95%
form
powder
bp
151 °C/20 mmHg (lit.)
mp
54-57 °C (lit.)
SMILES string
COC(=O)CCC(O)=O
InChI
1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)
InChI key
JDRMYOQETPMYQX-UHFFFAOYSA-N
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Isabelle Briaud et al.
Diabetes, 51(3), 662-668 (2002-03-02)
Chronic elevations in plasma levels of fatty acids (FAs) adversely affect pancreatic beta-cell function in type 2 diabetes. In vitro, we have previously shown that deleterious effects of prolonged exposure of isolated islets to FAs were dependent on the presence
D L Eizirik et al.
Molecular and cellular endocrinology, 118(1-2), 71-83 (1996-04-19)
Nitric oxide (NO) has been proposed as a possible mediator of beta-cell damage in human IDDM. This hypothesis is based on in vitro studies with rodent pancreatic islets. In the present study we examined whether human beta-cells are affected by
P Maechler et al.
The Journal of biological chemistry, 274(39), 27905-27913 (1999-09-17)
The effects of a transient exposure to hydrogen peroxide (10 min at 200 microM H(2)O(2)) on pancreatic beta cell signal transduction and insulin secretion have been evaluated. In rat islets, insulin secretion evoked by glucose (16.7 mM) or by the