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Merck

870451O

Avanti

2-OG

Avanti Research™ - A Croda Brand

Synonym(s):

2-oleoyl glycerol

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About This Item

Empirical Formula (Hill Notation):
C21H40O4
CAS Number:
3443-84-3
Molecular Weight:
356.54
MDL number:
MFCD00171536
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

2-OG, Avanti Research™ - A Croda Brand 870451O

SMILES string

[H]C(CO)(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO

InChI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI key

UPWGQKDVAURUGE-KTKRTIGZSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 5 mg (with screw cap/argon/foil bag (870451O-5mg))

manufacturer/tradename

Avanti Research™ - A Croda Brand 870451O

lipid type

phosphoglycerides
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

Application

2-oleoyl glycerol (2-OG) is suitable for use in a lipidomic study.

Biochem/physiol Actions

2-oleoyl glycerol (2-OG) acts as an agonist for G protein-coupled receptor 119 (GPR119) in vitro and stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo.

General description

2-oleoyl glycerol (2-OG) is synthesized from trioleoylglycerol from the reaction catalyzed from pancreatic lipase (PL).

Packaging

5 mL PTFE Vial with Screw Cap/Argon/Foil Bag (870451O-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen KB, et al.
The Journal of Clinical Endocrinology and Metabolism, 96(9), E1409-E1417 (2011)
Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides
Tortoriello G, et al.
PLoS ONE, 8(7), e67865-e67865 (2013)
Ieva Vasiliauskaité-Brooks et al.
Nature, 544(7648), 120-123 (2017-03-23)
Adiponectin receptors (ADIPORs) are integral membrane proteins that control glucose and lipid metabolism by mediating, at least in part, a cellular ceramidase activity that catalyses the hydrolysis of ceramide to produce sphingosine and a free fatty acid (FFA). The crystal

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