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Merck

8.52122

Fmoc-Asp(OAll)-OH

≥98.0% (acidimetric), for peptide synthesis, Novabiochem®

Synonym(s):

Fmoc-Asp(OAll)-OH

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About This Item

Empirical Formula (Hill Notation):
C22H21NO6
CAS Number:
Molecular Weight:
395.41
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
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Product Name

Fmoc-Asp(OAll)-OH, Novabiochem®

Quality Level

product line

Novabiochem®

assay

≥98% (TLC), ≥98.0% (HPLC), ≥98.0% (acidimetric)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

111-114 °C

application(s)

peptide synthesis

functional group

carboxylic acid

storage temp.

2-30°C

SMILES string

N([C@@H](CC(=O)OCC=C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C22H21NO6/c1-2-11-28-20(24)12-19(21(25)26)23-22(27)29-13-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h2-10,18-19H,1,11-13H2,(H,23,27)(H,25,26)/t19-/m0/s1

InChI key

FBNFRRNBFASDKS-IBGZPJMESA-N

General description

Orthogonally-protected building block for the synthesis of peptides modified at the Asp side chain by Fmoc SPPS. See entry for 852072 for more details.04-12-1303

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -30.0 - -25.0 °
Purity (TLC(157A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 1.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1303

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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