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Merck

46794

Sulfadimethoxine

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide

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About This Item

Empirical Formula (Hill Notation):
C12H14N4O4S
CAS Number:
122-11-2
Molecular Weight:
310.33
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757244
EC Number:
204-523-7
Beilstein/REAXYS Number:
306856
MDL number:
MFCD00057345

Product Name

Sulfadimethoxine, VETRANAL®, analytical standard

InChI key

ZZORFUFYDOWNEF-UHFFFAOYSA-N

InChI

1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

SMILES string

COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1

grade

analytical standard

agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

clinical testing

format

neat

mode of action

DNA synthesis | interferes
enzyme | inhibits

storage temp.

2-8°C

Quality Level

200

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfadimethoxine may be used as a reference standard in the determination of sulfadimethoxine in eggs using high performance liquid chromatography (HPLC).

General description

Chemical structure: sulfonamide
Sulfadimethoxine is an long acting sulfonamide antibiotic, which finds applications in pen-held lobsters, Homarus americanus for treatment of gaffkemia.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5962
BCCL9603
BCCL9553
BCCL5587
BCCK4645

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Rapid high-performance liquid chromatographic determining technique of sulfamonomethoxine, sulfadimethoxine, and sulfaquinoxaline in eggs without use of organic solvents.
Analytica Chimica Acta null
Photochemical fate of sulfadimethoxine in aquaculture waters.
Farusava N.
Environmental Science & Technology, 481(2), 255-259 (2003)
Disposition of sulfadimethoxine in the lobster (Homarus americanus).
OMJ and GMB
Veterinary and Human Toxicology, 30, 36-40 (1988)
Dan Liu et al.
Chemical & pharmaceutical bulletin, 59(1), 63-71 (2011-01-08)
Recently, dendrimers have been widely used in medical applications such as drug delivery and gene transfection. In this study, a pH-sensitive diblock copolymer of poly(methacryloyl sulfadimethoxine) (PSD) and polyethylene glycol (PEG) modified by lactose (LA-PEG-b-PSD) was synthesized. The pK(a) value
Ailiang Chen et al.
Biosensors & bioelectronics, 42, 419-425 (2012-12-12)
Quickly and sensitively detection of antibiotic residues in animal products often requires time-consuming techniques and expensive instrumentation. To address these limitations, a high sensitive aptasensor for sulfadimethoxine (SDM) using unmodified gold nanoparticles (AuNPs) was developed in the present study. The
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