78666
Taxifolin
analytical standard
Synonym(s):
(2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone, (2R,3R)-Dihydroquercetin
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About This Item
Empirical Formula (Hill Notation):
C15H12O7
CAS Number:
Molecular Weight:
304.25
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-543-4
Beilstein/REAXYS Number:
5299277
MDL number:
grade
analytical standard
Quality Level
assay
≥85% (HPLC)
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
SMILES string
O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3
InChI
1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1
InChI key
CXQWRCVTCMQVQX-LSDHHAIUSA-N
General description
Taxifolin is a plant flavonoid, which may find applications in the treatment of coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction and sequelae.
Application
Taxifolin can be used as a reference standard for the determination of taxifolin in plasma of rabbit using high performance liquid chromatography technique(HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid
Theriault A, et al.
Journal of Lipid Research, 41, 1969-1979 (2000)
Anita Elaine Weidmann
European journal of pharmacology, 684(1-3), 19-26 (2012-04-20)
Dihydroquercetin (taxifolin) is a potent flavonoid found in onions, French maritime bark, milk thistle, tamarind seeds and commercially available semi-synthetic monoHER marketed as Venoruton. This review focuses on the therapeutic promise of dihydroquercetin in major disease states such as cancer
Mijun Peng et al.
Environmental toxicology and pharmacology, 33(2), 327-333 (2012-02-04)
The effect of heavy metal ions, Cd(2+), Hg(2+) and Pb(2+) on taxifolin binding to bovine serum albumin (BSA) has been investigated by spectroscopic methods. The results indicated that the presence of heavy metal ions significantly affected the binding modes and