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Merck

R7635

Ronidazole

analytical standard

Synonym(s):

1-Methyl-2-(carbamoyloxymethyl)-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C6H8N4O4
CAS Number:
7681-76-7
Molecular Weight:
200.15
NACRES:
NA.24
PubChem Substance ID:
329823648
UNSPSC Code:
41116107
EC Number:
231-675-1
MDL number:
MFCD00133801

Key Documents

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Product Name

Ronidazole, analytical standard

InChI key

PQFRTXSWDXZRRS-UHFFFAOYSA-N

InChI

1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)

SMILES string

Cn1c(COC(N)=O)ncc1N(=O)=O

grade

analytical standard

assay

≥95%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

Quality Level

100

Related Categories

Application

Ronidazole may be used as a reference standard in the determination of the analyte in poultry muscle and eggs using high-performance liquid chromatography with ultraviolet detection and confirmatory analysis by atmospheric pressure chemical ionization-mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Ronidazole is a nitroimidazole compound, commonly used as antiprotozoal and antibacterial agent.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT7186
MKCS7829
MKCS3424
MKCM1762
MKCH9347

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Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.
Hoffer Max and Grunberg E
Journal of Medicinal Chemistry, 17(9), 1019-1020 (1974)
Elizabeth J Kather et al.
Journal of veterinary internal medicine, 21(5), 966-970 (2007-10-18)
The nitroimidazole, ronidazole, has been demonstrated to have in vitro and in vivo activity against the protozoan Tritrichomonas foetus in cats. The purpose of this study was to evaluate the in vitro susceptibility of feline T. foetus isolates obtained from
Neurotoxicosis in 4 cats receiving ronidazole.
Terri W Rosado et al.
Journal of veterinary internal medicine, 21(2), 328-331 (2007-04-13)
Determination of dimetridazole, ronidazole and their common metabolite in poultry muscle and eggs by high performance liquid chromatography with UV detection and confirmatory analysis by atmospheric pressure chemical ionisation mass spectrometry.
Sams JM, et al.
Analyst, 123(1-2), 2545-2549 (1998)
I Burgener et al.
Schweizer Archiv fur Tierheilkunde, 151(8), 383-389 (2009-08-05)
Recent reports identified Tritrichomonas fetus, the causative agent of bovine trichomonosis, in cats with large-bowel diarrhea in the US. Between July 2007 and August 2008, a total of 105 Swiss cats were tested for T. fetus with the InPouchTM culture
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