V0500
L-Valine
≥98% (HPLC), suitable for thin layer chromatography (TLC)
Synonym(s):
(S)-α-Aminoisovaleric acid, L-2-Amino-3-methylbutanoic acid
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About This Item
Linear Formula:
(CH3)2CHCH(NH2)CO2H
CAS Number:
Molecular Weight:
117.15
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-773-6
MDL number:
Beilstein/REAXYS Number:
1721136
Product Name
L-Valine, reagent grade, ≥98% (HPLC)
grade
reagent grade
Quality Level
assay
≥98% (HPLC)
form
powder
technique(s)
thin layer chromatography (TLC): suitable
color
white
mp
295-300 °C (subl.) (lit.)
solubility
H2O: 50 mg/mL, clear, colorless
SMILES string
CC(C)[C@H](N)C(O)=O
InChI
1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
InChI key
KZSNJWFQEVHDMF-BYPYZUCNSA-N
Application
- L-Valine has been used as a standard in thin layer chromatography.
- It has been used as a supplement in Grace′s antheraea medium for the culture of cells and tissue from invertebrates.
- It has been used in the preparation of starvation media to study the role of relA gene in antibiotic resistance in E. coli.
Biochem/physiol Actions
Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA) maintains a balance among the BCAAs. L-Valine serves as an energy fuel. Long term deficiency of L-Valine leads to growth failure, organ damage and loss of muscle mass.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Martin Kohlmeier
Nutrient Metabolism: Structures, Functions, and Genes, 390-390 (2015)
Preparation of several media for the culture of tissues and cells from invertebrates.
Vaughn
TCA Manual, 527-537 (1977)
On the limited role of relA in kanamycin and amino acid starvation induced stringency and subsequent antibiotic cross-protection in Escherichia coli
Chiang
Journal of Experimental Microbiology and Immunology, 15, 59-63 (2011)