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Merck

14470

1,4-Bis(acryloyl)piperazine

BioXtra, suitable for electrophoresis, ≥99.0% (TLC)

Synonym(s):

1,4-Di(acryloyl)piperazine, N,N′-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide

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About This Item

Empirical Formula (Hill Notation):
C10H14N2O2
CAS Number:
Molecular Weight:
194.23
UNSPSC Code:
41105319
NACRES:
NA.26
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
745431
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product line

BioXtra

Quality Segment

assay

≥99.0% (TLC)

form

solid

technique(s)

electrophoresis: suitable

impurities

≤0.05% free acrylic acid

mp

91.5-93.5 °C (lit.)

anion traces

chloride (Cl-): ≤200 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

suitability

suitable for electrophoresis

storage temp.

2-8°C

SMILES string

C=CC(=O)N1CCN(CC1)C(=O)C=C

InChI

1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2

InChI key

YERHJBPPDGHCRJ-UHFFFAOYSA-N

Application


  • Fabrication and application of zwitterionic phosphorylcholine functionalized monoliths with different hydrophilic crosslinkers in hydrophilic interaction chromatography: This study demonstrates the effective use of 1,4-Bis(acryloyl)piperazine as a crosslinker in creating zwitterionic monoliths for chromatographic applications, highlighting its utility in enhancing polymer interactions and selectivity in separation processes (Wang et al., 2020).

  • Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles: This application uses a derivative concept where 1,4-Bis(acryloyl)piperazine could theoretically enhance the self-assembly and stability of redox-sensitive polymeric nanoparticles, offering insights into controlled release and targeted drug delivery systems (Ranucci et al., 2008).

Other Notes

Used as a vinylating agent for graft-copolymerization of different enzymes to cellulose, dextran, or starch; New crosslinking agent for polyacrylamide gels with improved protein separation and detection by silver staining; Increased resolution in 2D-protein electrophoresis.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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