24368C
EX-CELL® Advanced CHO Feed 1 (without glucose)
Synonym(s):
EX-CELL® Advanced CHO Feed 1
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About This Item
NACRES:
NA.71
UNSPSC Code:
12352200
Product Name
EX-CELL® Advanced, CHO Feed 1 (without glucose). Use 34.10 g/L. See information sheet, 24368C @ www.sigmaaldrich.com for hydration instructions
Quality Level
product line
EX-CELL®
form
dry powder
technique(s)
cell culture | mammalian: suitable (suspension)
shipped in
ambient
storage temp.
2-8°C
General description
EX-CELL® Advanced CHO Feed 1 (without glucose) is chemically-defined and contains no animal derived components. This feed is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Fed-batch Medium (14366C or 24366C). This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME).
Preparation Note
Formulated to contain 34.1 grams of powder per liter of medium.
Other Notes
Submit the EX-CELL Advanced CHO Fed-batch request form to get in touch with a SAFC representative.
Legal Information
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
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Pao-Chun Lin et al.
mAbs, 11(5), 965-976 (2019-05-03)
Chinese hamster ovary (CHO) cells are the biopharmaceutical industry's primary means of manufacturing therapeutic proteins, including monoclonal antibodies. The major challenge in cell line development for the production of recombinant biopharmaceuticals lies in generating and isolating rare high-producing stable clones