82435
Puerarin
≥98.0% (HPLC)
Synonym(s):
8-(β-D-Glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kakonein
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About This Item
Empirical Formula (Hill Notation):
C21H20O9
CAS Number:
Molecular Weight:
416.38
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
64198
Quality Level
assay
≥98.0% (HPLC)
form
powder
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)ccc3C(=O)C(=COc23)c4ccc(O)cc4
InChI
1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1
InChI key
HKEAFJYKMMKDOR-VPRICQMDSA-N
Gene Information
mouse ... Aldh1a2(19378), Maoa(17161)
Biochem/physiol Actions
Isoflavone component of kudzu. Reduces anxiety symptoms associated with alcohol withdrawal.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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David H Overstreet et al.
Pharmacology, biochemistry, and behavior, 75(3), 619-625 (2003-08-05)
Because extracts of kudzu have been used as a hangover remedy in China for many centuries, we tested the ability of NPI-031G (puerarin), an isoflavone isolated from kudzu, to counteract anxiogenic effects associated with withdrawal from chronic alcohol exposure. NPI-O31G
Wen Cheng et al.
PloS one, 7(9), e45529-e45529 (2012-10-03)
Puerarin is a major isoflavonoid compound extracted from Radix puerariae. It has a weak estrogenic action by binding to estrogen receptors (ERs). In our early clinical practice to treat endometriosis, a better therapeutic effect was achieved if the formula of
Xin-Yi Liu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(22), 3391-3394 (2013-02-05)
To detect the stability of PEGylated puerarin (PEG-PUE), in order to provide experimental basis for storage conditions of PEGylated puerarin. First, a method for determining the content of PEG-PUE was established. Next, a system study was conducted for the stability