89270
Thymidine
≥99.0% (HPLC), synthetic, powder
Synonym(s):
1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, 1-(2-Deoxy-β-D-ribofuranosyl)thymine, 2′-Deoxythymidine, Thymine deoxyriboside, dT
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About This Item
Empirical Formula (Hill Notation):
C10H14N2O5
CAS Number:
Molecular Weight:
242.23
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-070-4
MDL number:
Beilstein/REAXYS Number:
89285
Assay:
≥99.0% (HPLC)
Biological source:
synthetic
Form:
powder
Solubility:
hot water: 1 g/10 mL
Product Name
Thymidine, ≥99.0% (HPLC)
biological source
synthetic
Quality Level
assay
≥99.0% (HPLC)
form
powder
optical activity
[α]20/D +19±1°, c = 1% in H2O
mp
185-190 °C, 186-188 °C (lit.)
solubility
hot water: 1 g/10 mL
SMILES string
CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O
InChI
1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChI key
IQFYYKKMVGJFEH-XLPZGREQSA-N
Application
Thymidine has been used:
- to culture human fibroblast cell lines.
- in in vitro wound healing assay.
- to culture various cancer cell lines.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Edward J Gane et al.
Gastroenterology, 146(1), 138-146 (2013-09-27)
There is a close relationship between chronic hepatitis B virus infection and chronic renal disease. We analyzed changes in renal function using different markers of glomerular filtration rate (GFR) in multiple studies of telbivudine treatment of patients with chronic hepatitis
Anne P Bouvy et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 29(8), 1587-1597 (2014-04-29)
To evaluate the influence of induction therapy on Tregs we investigated their origin, kinetics and function in kidney transplant patients after treatment with T-cell depleting rabbit antithymocyte globulin (rATG) or IL-2 receptor antagonist basiliximab. Flow cytometry was used to study
Yee Suan Poo et al.
PLoS neglected tropical diseases, 8(12), e3354-e3354 (2014-12-05)
The recent epidemic of the arthritogenic alphavirus, chikungunya virus (CHIKV) has prompted a quest to understand the correlates of protection against virus and disease in order to inform development of new interventions. Herein we highlight the propensity of CHIKV infections