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Merck

A1422

p-Aminohippuric acid

≥99%

Synonym(s):

4-Aminohippuric acid, N-(4-Aminobenzoyl)glycine

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About This Item

Linear Formula:
NH2C6H4C(O)NHCH2COOH
CAS Number:
Molecular Weight:
194.19
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-518-9
MDL number:
Beilstein/REAXYS Number:
1213676
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Product Name

p-Aminohippuric acid, ≥99%

Quality Level

assay

≥99%

form

powder

mp

199-200 °C (dec.) (lit.)

application(s)

cell analysis

storage temp.

room temp

SMILES string

Nc1ccc(cc1)C(=O)NCC(O)=O

InChI

1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13)

InChI key

HSMNQINEKMPTIC-UHFFFAOYSA-N

General description

Renal tubules secretes para amino hippuric acid/PAH.

Application

p-Aminohippuric acid has been used as infusions to measure plasma flow.

Biochem/physiol Actions

Para-aminohippuric acid (PAH) is used as a marker in nutrition studies to measure the flow of blood in pigs, which inturn helps to determine the portal-drained viscera (PDV) flux of nutrients.
Para-Aminohippuric acid (PAH), OAT-1 specific, is used to help differentiate and characterized organic anion transporter (OAT) isoforms.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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In vivo measurement of nitric oxide production in porcine gut, liver and muscle during hyperdynamic endotoxaemia
Bruins MJ, et al.
British Journal of Pharmacology, 137(8), 1225-1236 (2002)
Influence of para-aminohippuric acid analysis on net portal-drained viscera flux of nutrients in pigs
Fernandez-FI, et al.
Animal : An International Journal of Animal Bioscience, 12(2), 232-238 (2018)
Glomerular Filtration
Quantitative Human Physiology, 633-641 (2012)