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Merck

A6435

Aluminum potassium sulfate dodecahydrate

BioReagent, suitable for insect cell culture

Synonym(s):

Alum, Potassium alum, Potassium aluminum sulfate dodecahydrate

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About This Item

Linear Formula:
AlK(SO4)2 · 12H2O
CAS Number:
7784-24-9
Molecular Weight:
474.39
NACRES:
NA.71
PubChem Substance ID:
24891090
UNSPSC Code:
12352207
EC Number:
233-141-3
MDL number:
MFCD00149143
Assay:
≥98%
Form:
powder

Key Documents

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product line

BioReagent

Quality Level

200

assay

≥98%

form

powder

technique(s)

cell culture | insect: suitable

mp

92 °C (lit.)

density

1.757 g/mL at 25 °C (lit.)

SMILES string

O.O.O.O.O.O.O.O.O.O.O.O.[Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

1S/Al.K.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;;2*(H2,1,2,3,4);12*1H2/q+3;+1;;;;;;;;;;;;;;/p-4

InChI key

GNHOJBNSNUXZQA-UHFFFAOYSA-J

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Application

Aluminum potassium sulfate dodecahydrate has been used as an adjuvant of ovalbumin to induce anaphylaxis in mice.

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000364211
0000364211
SLCH6745
SLCD3155
SLBZ8266

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Epinephrine inhibits vascular hyperpermeability during platelet-activating factor-or ovalbumin-induced anaphylaxis
Ma, X, et al.
Royal Society of Chemistry Advances, 7(83), 52762-52771 (2017)
Upasana Ray et al.
Science translational medicine, 7(306), 306ra151-306ra151 (2015-09-25)
JC polyomavirus (JCV) persistently infects the urinary tract of most adults. Under conditions of immune impairment, JCV causes an opportunistic brain disease, progressive multifocal leukoencephalopathy (PML). JCV strains found in the cerebrospinal fluid of PML patients contain distinctive mutations in
K Yadava et al.
Allergy, 69(10), 1333-1342 (2014-06-26)
Thymic stromal lymphopoietin (TSLP) is a cytokine primarily produced by epithelial cells, which has been shown to be a potent inducer of T-helper 2 (Th2)-type responses. However, TSLP has pleiotropic effects upon immune cells, and although extensively studied in the
Saya Moriyama et al.
The Journal of experimental medicine, 211(7), 1297-1305 (2014-06-11)
Follicular helper T (Tfh) cells access the B cell follicle to promote antibody responses and are particularly important for germinal center (GC) reactions. However, the molecular mechanisms of how Tfh cells are physically associated with GCs are incompletely understood. We
Yan-Feng Li et al.
Nature communications, 5, 4273-4273 (2014-07-01)
Germline or B-cell-specific loss of Ptpn6 gene encoding the Shp1 protein tyrosine phosphatase leads to skewed B lymphopoiesis and systemic autoimmunity. Here, to study its role in B-cell terminal differentiation, we generated Ptpn6(f/f)Aicda(Cre/+) mice with Shp1 ablated only in activated
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