A7219
L -Aspartic acid
from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
Synonym(s):
(S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid
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About This Item
Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
133.10
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-291-6
MDL number:
Beilstein/REAXYS Number:
1723530
biological source
non-animal source
Quality Segment
agency
meets EP testing specifications, meets USP testing specifications
assay
98.5-101.0%
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white to off-white
mp
>300 °C (dec.) (lit.)
solubility
1 M HCl: 100 mg/mL
SMILES string
N[C@@H](CC(O)=O)C(O)=O
InChI
1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI key
CKLJMWTZIZZHCS-REOHCLBHSA-N
Gene Information
human ... CA1(759), CA2(760)
rat ... Grin2a(24409)
General description
Aspartic acid(ASP)/aspartate, a non-essential amino acid, is naturally produced by mammals. ASP is one of the 20 building-block amino acids of proteins and has a one letter code, D. L-Aspartic acid can be manufactured industrially by an enzymatic process using the aspartase enzyme.
Application
L-Aspartic acid has been used:
- as an aspartame (ASP) metabolite to determine acetylcholinesterase (AChE) activity in the hippocampal homogenate of suckling rats
- as printed chemotaxis ligands to screen chemotaxis receptors with high-throughput technologies and verify the interactions with surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR)
- as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) for supplementation assays of various cultured cell lines
Biochem/physiol Actions
Principal neurotransmitter for fast synaptic excitation.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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