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Merck

C3011

Cesium chloride

Grade I, ≥99.0%

Synonym(s):

Caesium monochloride, Cesium chloride

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About This Item

Linear Formula:
CsCl
CAS Number:
Molecular Weight:
168.36
NACRES:
NA.75
PubChem Substance ID:
UNSPSC Code:
12352207
EC Number:
231-600-2
MDL number:
Assay:
≥99.0%
Form:
powder
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Product Name

Cesium chloride, Grade I, ≥99.0%

InChI key

AIYUHDOJVYHVIT-UHFFFAOYSA-M

InChI

1S/ClH.Cs/h1H;/q;+1/p-1

SMILES string

[Cl-].[Cs+]

type

Grade I

assay

≥99.0%

form

powder

mp

645 °C (lit.)

absorption

≤0.2 at 280 in H2O at 50%

application(s)

hematology
histology

Quality Level

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Analysis Note

Solutions may contain a slight haze.

Application

Cesium chloride has been used as a component of pipette solution, to record mechanosensitive currents in dorsal root ganglia neurons. It has been used in patch clamping to study neurons in intact myenteric ganglia.
Used for the preparation of electrically conducting glasses.Used to make solutions for the separation of RNA from DNA by density gradient centrifugation.

Biochem/physiol Actions

Oral intake of cesium chloride is known to increase the pH in cancer cells. Mild toxicity of cesium chloride might cause hypotension, gastrointestinal distress, numbness and syncope. It also leads to severe hypokalemia, hypomagnesemia, acute heart attack and polymorphic ventricular tachycardia in episodes.

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator
Jizhe H, et al.
Nature Protocols, 6(7), 979-979 (2011)
Patch clamp recording from enteric neurons in situ
Nancy O, et al.
Nature Protocols, 6(1), 15-15 (2011)
Petr Melnikov et al.
Biological trace element research, 135(1-3), 1-9 (2009-08-06)
The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However
Philippe Jean et al.
Nature communications, 11(1), 3208-3208 (2020-06-27)
Inner hair cells (IHCs) are the primary receptors for hearing. They are housed in the cochlea and convey sound information to the brain via synapses with the auditory nerve. IHCs have been thought to be electrically and metabolically independent from
Tuan A Ho et al.
Langmuir : the ACS journal of surfaces and colloids, 28(2), 1256-1266 (2011-12-14)
All-atom molecular dynamics simulations were conducted to study the dynamics of aqueous electrolyte solutions confined in slit-shaped silica nanopores of various degrees of protonation. Five degrees of protonation were prepared by randomly removing surface hydrogen atoms from fully protonated crystalline

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