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Merck

C5914

Cell Dissociation Solution Non-enzymatic 1x

Prepared in phosphate buffered saline without calcium and magnesium, sterile-filtered, BioReagent, suitable for cell culture

Synonym(s):

Dissociation Solution

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.75
MDL number:
Concentration:
1 ×
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Quality Level

sterility

sterile-filtered

product line

BioReagent

form

liquid

concentration

1 ×

technique(s)

cell culture | mammalian: suitable

pH

6.9-7.1

shipped in

wet ice

storage temp.

2-8°C

General description

Cell dissociation by non-enzymatic methods in human mesenchymal stromal cells aid in their detachment and preserves their functionality especially the expression of cell surface chemokine receptor.

Application

Special non-enzymatic formulation for gently dislodging adherent cell types from plastic or glass surfaces.
Cell Dissociation Solution Non-enzymatic 1x has been used for the dissociation of retinal astrocytes culture, U87 glioblastoma tumor cells and cardiac stem cells (CSCs).


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flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2



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Ineke D C Jansen et al.
International journal of molecular sciences, 21(17) (2020-08-29)
Lysosome associated membrane proteins (LAMPs) are involved in several processes, among which is fusion of lysosomes with phagosomes. For the formation of multinucleated osteoclasts, the interaction between receptor activator of nuclear kappa β (RANK) and its ligand RANKL is essential.
Non-enzymatic dissociation of human mesenchymal stromal cells improves chemokine-dependent migration and maintains immunosuppressive function
Garg A, et al.
Cytotherapy, 16(4), 545-559 (2014)
Human cardiac stem cells with reduced notch signaling show enhanced therapeutic potential in a rat acute infarction model
Matsuda T, et al.
Circulation Journal, 78(1), 222-231 (2014)



Global Trade Item Number

SKUGTIN
C591404053252368790