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Merck

D2631

Dihexadecyl phosphate

Synonym(s):

DHP, Dicetyl phosphate

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About This Item

Linear Formula:
[CH3(CH2)15O]2P(O)OH
CAS Number:
2197-63-9
Molecular Weight:
546.85
UNSPSC Code:
51191904
NACRES:
NA.25
PubChem Substance ID:
24893702
EC Number:
218-594-7
Beilstein/REAXYS Number:
1717117
MDL number:
MFCD00008999

Key Documents

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InChI key

RNPXCFINMKSQPQ-UHFFFAOYSA-N

InChI

1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)

SMILES string

OP(OCCCCCCCCCCCCCCCC)(OCCCCCCCCCCCCCCCC)=O

description

anionic

form

powder

mol wt

546.85 g/mol

technique(s)

DNA extraction: suitable

mp

74-75 °C (lit.)

lipid type

phospholipids

storage temp.

−20°C

Quality Level

100

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Related Categories

Biochem/physiol Actions

Dihexadecyl phosphate (DHP) is a negatively charged lipid that is used for the formation of model membranes.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9457
STBH2863
STBF1961V
STBD1149V
STBB5281V

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Hamdy Abdelkader et al.
Journal of pharmaceutical sciences, 100(5), 1833-1846 (2011-01-20)
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as
Kenji Suda et al.
Journal of controlled release : official journal of the Controlled Release Society, 266, 301-309 (2017-10-11)
Age-related macular degeneration (AMD), in which choroidal neovascularization (CNV) affects the center of the retina (macula), leads to the irreversible visual loss. The intravitreal injection of anti-angiogenesis antibodies improved the prognosis of AMD, but relatively less invasive therapies should be
Ba Hieu Tran et al.
International journal of nanomedicine, 14, 10061-10077 (2020-01-11)
S-propargyl-cysteine (SPRC; alternatively known as ZYZ-802) is a novel modulator of endogenous tissue H2S concentrations with known cardioprotective and anti-inflammatory effects. However, its rapid metabolism and excretion have limited its clinical application. To overcome these issues, we have developed some
Abbas Pardakhty et al.
International journal of pharmaceutics, 328(2), 130-141 (2006-09-26)
In this study, niosomes of polyoxyethylene alkyl ethers (Brij) were prepared for encapsulation of insulin by film hydration method. Without cholesterol, brij 35 and brij 58 did not form niosomes, apparently because of relatively large polar head groups in comparison
Haruyuki Ishii et al.
Colloids and surfaces. B, Biointerfaces, 92, 372-376 (2011-12-16)
Hollow silica particle was obtained with a vesicle template synthesis in water under ambient conditions in the presence of ammonia. Biomimetic vesicles, liposomes were used, which consisted of a zwitterionic phospholipid, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and a tiny amount of charged amphiphiles
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