F7876
Folic acid
≥97%
Synonym(s):
PteGlu, Pteroyl-L-glutamic acid, Vitamin M
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C19H19N7O6
CAS Number:
Molecular Weight:
441.40
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058014
UNSPSC Code:
12352106
EC Number:
200-419-0
MDL number:
Beilstein/REAXYS Number:
100781
biological source
synthetic (organic)
Quality Level
assay
≥97%
form
powder
technique(s)
HPLC: suitable
color
faint orange to dark orange-yellow, faint yellow to dark yellow
mp
>285 °C
storage temp.
room temp
SMILES string
NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
InChI
1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChI key
OVBPIULPVIDEAO-LBPRGKRZSA-N
Application
Folic acid has been used:
- to induce acute kidney injury in mice
- as a supplement to cultivate MCF-7 breast cancer cells.
- to construct folate or TNF-related apoptosis-including ligand (TRAIL)-conjugated nanomicelles
Biochem/physiol Actions
Enzyme cofactor essential for the synthesis, methylation, and repair of DNA. Folic acid supplements may reduce colorectal cancer risk.
Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon′ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
Still not finding the right product?
Explore all of our products under Folic acid
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
Surface-enhanced Raman spectroscopy of cell lysates mixed with silver nanoparticles for tumor classification.
Hassoun M, et al.
Beilstein Journal of Nanotechnology, 8, 1183-1183 (2017)
Romain Froquet et al.
Nature protocols, 4(1), 25-30 (2009-01-10)
Dictyostelium amoebae have been used as a host model to measure virulence of a wide range of bacterial pathogens. The simple protocol described here takes advantage of the ability of Dictyostelium to grow and form plaques on a lawn of
Novel water-borne polyurethane nanomicelles for cancer chemotherapy: higher efficiency of folate receptors than TRAIL receptors in a Cancerous Balb/C Mouse Model.
Ajorlou E, et al.
Pharmaceutical Research, 33(6), 1426-1439 (2016)