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Merck

H0377

DL-5-Hydroxylysine hydrochloride

≥98% (TLC)

Synonym(s):

2,6-Diamino-5-hydroxycaproic acid hydrochloride, 2,6-Diamino-5-hydroxyhexanoic acid hydrochloride

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About This Item

Linear Formula:
NH2CH2CH(OH)CH2CH2CH(NH2)COOH · HCl
CAS Number:
13204-98-3
Molecular Weight:
198.65
NACRES:
NA.26
PubChem Substance ID:
24895397
UNSPSC Code:
12352209
EC Number:
236-168-9
MDL number:
MFCD00012878
Beilstein/REAXYS Number:
3914368

Key Documents

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Product Name

DL-5-Hydroxylysine hydrochloride,

InChI key

MJXVOTKVFFAZQJ-UHFFFAOYSA-N

InChI

1S/C6H14N2O3.ClH/c7-3-4(9)1-2-5(8)6(10)11;/h4-5,9H,1-3,7-8H2,(H,10,11);1H

SMILES string

Cl.NCC(O)CCC(N)C(O)=O

assay

≥98% (TLC)

form

powder

color

white

mp

225 °C (dec.) (lit.)

application(s)

detection
peptide synthesis

Quality Level

200

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Related Categories

Application


  • Characterization of acetyl-CoA: L-lysine N6-acetyltransferase, which catalyses the first step of carbon catabolism from lysine in Saccharomyces cerevisiae.: This research investigates the enzyme acetyl-CoA: L-lysine N6-acetyltransferase, which initiates the catabolism of lysine in Saccharomyces cerevisiae. Utilizing DL-5-Hydroxylysine hydrochloride, the study provides insights into the metabolic pathways and regulatory mechanisms of lysine degradation, contributing to the broader understanding of amino acid metabolism in yeast (Bode et al., 1993).

Biochem/physiol Actions

DL-5-Hydroxylysine is a racemic mixture of D- and L- enantiomers of 5-hydroxylysine which may be used as potential target markers for radical-induced protein oxidation.

Other Notes

Mixed DL and DL-allo

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN1721
BCCL2534
BCCH1268
BCCJ0881
BCCD9243

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E R Stadtman et al.
Amino acids, 25(3-4), 207-218 (2003-12-09)
We summarize here results of studies designed to elucidate basic mechanisms of reactive oxygen (ROS)-mediated oxidation of proteins and free amino acids. These studies have shown that oxidation of proteins can lead to hydroxylation of aromatic groups and aliphatic amino
R Bode et al.
Archives of microbiology, 160(5), 397-400 (1993-01-01)
The carbon catabolism of L-lysine starts in Saccharomyces cerevisiae with acetylation by an acetyl-CoA:L-lysine N6-acetyltransferase. The enzyme is strongly induced in cells grown on L-lysine as sole carbon source and has been purified about 530-fold. Its activity was specific for
Giuseppe Forlani et al.
Frontiers in plant science, 11, 582026-582026 (2020-11-17)
Because proline accumulates rapidly in response to several stress conditions such as drought and excess salt, increased intracellular levels of free proline are considered a hallmark of adaptive reactions in plants, particularly in response to water stress. Proline quantitation is
Rafal Mól et al.
Plant & cell physiology, 45(10), 1396-1405 (2004-11-27)
The role of ethylene and auxin in stigma-to-ovule signalling was investigated in maize (Zea mays L.). Maturation of the egg cells in an ear was stimulated before actual fertilization by the application of fresh pollen grains or quartz sand to
Nenggang Zhang et al.
Physiologia plantarum, 116(3), 383-388 (2003-01-25)
We studied the mode of action of 4,4,4-trifluoro-3- (indole-3-) butyric acid (TFIBA), a recently described root growth stimulator, on primary root growth of Lactuca sativa L. seedlings. TFIBA (100 micromoles) promoted elongation of primary roots by 40% in 72 h
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