M1778
Mucin from porcine stomach
Type III, bound sialic acid 0.5-1.5 %, partially purified powder
Synonym(s):
MUC
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About This Item
Form:
partially purified powder
Biological source:
Porcine stomach
biological source
Porcine stomach
Quality Level
type
Type III
form
partially purified powder
composition
bound sialic acid, 0.5-1.5%
technique(s)
microbiological culture: suitable
solubility
NaOH: soluble 20 mg/mL
storage temp.
2-8°C
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General description
Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.
Application
Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.
Biochem/physiol Actions
Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.
Preparation Note
Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Kenny C Mok et al.
mBio, 11(6) (2020-12-10)
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use
Leyuan Li et al.
Microbiome, 8(1), 33-33 (2020-03-13)
Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
C A Saceanu et al.
Journal of clinical microbiology, 31(9), 2371-2374 (1993-09-01)
Early identification and isolation of tuberculosis patients is of utmost importance to minimize the risk of further epidemic spread of the disease. The traditional concentrated acid-fast smears are not very reliable tools for the presumptive diagnosis of tuberculosis. Acid-fast bacillus
Francisco J Alvarez et al.
Applied and environmental microbiology, 81(8), 2770-2780 (2015-02-11)
The pathogenic fungus Candida albicans is the leading cause of vulvovaginal candidiasis (VVC). VVC represents a major quality-of-life issue for women during their reproductive years, a stage of life where the vaginal epithelium is subject to periodic hormonally induced changes
Helen Rose et al.
The Journal of antimicrobial chemotherapy, 63(3), 502-510 (2009-01-21)
The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated
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