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Merck

P8759

Pyrogallol Red

Powder

Synonym(s):

Pyrogallolsulfonephthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12O8S
CAS Number:
Molecular Weight:
400.36
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
251-134-3
MDL number:
Beilstein/REAXYS Number:
61394

Product Name

Pyrogallol Red, Suitable for use as a complexometric indicator

form

powder

InChI

1S/C19H12O8S/c20-12-7-5-10-17(15(12)22)26-18-11(6-8-13(21)16(18)23)19(10)9-3-1-2-4-14(9)28(24,25)27-19/h1-8,20-23H

InChI key

KUQNCHZOCSYKOR-UHFFFAOYSA-N

SMILES string

Oc1ccc2c(Oc3c(O)c(O)ccc3C24OS(=O)(=O)c5ccccc45)c1O

technique(s)

titration: suitable

color

green to very dark green, and brown

mp

≥300 °C (lit.)

solubility

1 M NH4OH: 10 mg/mL, clear

εmax

≥450 at 475 nm in methanol

suitability

suitable for complexometric indicator

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

Pyrogallol Red is suitable to prepare Fujita and Watanabe dye reagent used in Pyrogallol Red-Molybdenum (IV) complex (PR) method for the determination and quantification of urinary proteins.

General description

Pyrogallol red (PGR) is an ortho-diphenolic dye. It has high reactivity towards reactive oxygen species (ROS) and reactive nitrogen species (RNS) that include peroxynitrite, radical, peroxyl radicals, hypochlorite & superoxide anion.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Piyali Chatterjee et al.
PloS one, 7(7), e41884-e41884 (2012-08-01)
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal immune system activation, inflammation, and endothelial dysfunction. Toll-like receptor (TLR) 3 activation by double-stranded RNA (dsRNA) and TLR7/8 activation by single-stranded RNA (ssRNA) expressed by viruses and/or released from
Juan David Figueroa et al.
Redox biology, 24, 101207-101207 (2019-05-19)
Carbonate radicals (CO3-) are generated by the bicarbonate-dependent peroxidase activity of cytosolic superoxide dismutase (Cu,Zn-SOD, SOD-1). The present work explored the use of bleaching of pyrogallol red (PGR) dye to quantify the rate of CO3- formation from bovine and human
Yo Omata et al.
Journal of agricultural and food chemistry, 56(9), 3386-3390 (2008-04-09)
The radical-scavenging antioxidants play an important role against oxidative stress in the defense system in vivo. The beneficial effects of antioxidants contained in foods and beverages have been well-accepted, and their antioxidant capacity has been assessed by various methods. In
Randolph B Caldwell et al.
Applied and environmental microbiology, 70(1), 610-612 (2004-01-09)
A simple and reliable method for precipitating protein from bacterial culture supernatants based on a pyrogallol red-molybdate-methanol (PRMM) protocol has been developed and applied for the analysis of proteins secreted by a bacterial type III secretion system. PRMM-based precipitation has
Molecules-Kinetics of the Reaction of Pyrogallol Red, a Polyphenolic Dye, with Nitrous Acid: Role of NO and NO2
Molecules (Basel) null

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