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Merck

PLA0161

Rabbit anti-MOF/MYST1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

FLJ14040, K(lysine) acetyltransferase 8, Lysine acetyltransferase 8, MOF, MOZ, MYST histone acetyltransferase 1, MYST-1, MYST1, SAS2 and TIP60 protein 1, YBF2/SAS3, ZC2HC8, hMOF, histone acetyltransferase MYST1, ortholog of Drosophila males absent on the first (MOF), probable histone acetyltransferase MYST1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Species reactivity:
human, mouse
Citations:
1
Technique(s):
immunohistochemistry: 1:500- 1:2,000, immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:1,000- 1:10,000

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:500- 1:2,000, immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:1,000- 1:10,000

accession no.

BAB13924.1

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... MOF/MYST1(84148)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0161 maps to a region between residue 1 and 50 of human males absent on the first (MYST histone acetyltransferase 1) using the numbering given in entry BAB13924.1 (GeneID 84148).

Other Notes

MOF is a member of the MYST family of histone acetyltransferases (HAT). MOF has been shown to be required for histone H4 lysine K16-specific acetylation. MOF interacts with ATM (ataxia-telangiectasia-mutated) and may participate in the activation of ATM in response to DNA damage.

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
2

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Mzwanele Ngubo et al.
Aging cell, 23(7), e14150-e14150 (2024-04-05)
Hutchinson-Gilford Progeria syndrome (HGPS) is a lethal premature aging disorder caused by a de novo heterozygous mutation that leads to the accumulation of a splicing isoform of Lamin A termed progerin. Progerin expression deregulates the organization of the nuclear lamina

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