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Merck

S9381

Succinimide

99.1%

Synonym(s):

2,5-Pyrrolidinedione

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About This Item

Empirical Formula (Hill Notation):
C4H5NO2
CAS Number:
Molecular Weight:
99.09
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
204-635-6
MDL number:
Beilstein/REAXYS Number:
108440
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Product Name

Succinimide,

InChI

1S/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)

InChI key

KZNICNPSHKQLFF-UHFFFAOYSA-N

SMILES string

O=C1CCC(=O)N1

assay

99.1%

form

powder or crystals

color

white to off-white

bp

285-290 °C (lit.)

mp

123-125 °C (lit.)

Quality Level

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Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


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Yutaka Sadakane et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3240-3246 (2011-04-08)
The major soluble eye lens protein, αA-crystallin, has a very long half-life. Thus, many post-translational modifications, including stereoinversion, have been found in its constituent amino acids. We determine the rates of β-linkage isomerization, which is the main reaction through the
Yann Desfougères et al.
Biomacromolecules, 12(1), 156-166 (2010-12-21)
Protein chemical degradations occur naturally into living cells as soon as proteins have been synthesized. Among these modifications, deamidation of asparagine or glutamine residues has been extensively studied, whereas the intermediate state, a succinimide derivative, was poorly investigated because of
Ohgi Takahashi et al.
Chemistry & biodiversity, 7(6), 1630-1633 (2010-06-22)
The rapid racemization of aspartic acid (Asp) residues in peptides and proteins is due mainly to the succinimide intermediate. However, there should be another mechanism for Asp racemization without intermediacy of the succinimide. The direct H-atom abstraction from the C(alpha)-atom
Srinivasa Reddy Mothe et al.
The Journal of organic chemistry, 76(8), 2521-2531 (2011-03-15)
A one-pot, two-step method to prepare 3-halohydrofurans efficiently by TfOH-catalyzed hydroxylation/halocyclization of cyclopropyl methanols with H(2)O and N-halosuccinimide (NXS, X=1, Br, Cl) or Selectfluor is described. The reactions proceed rapidly under mild and operationally straightforward conditions with a catalyst loading
David Rennison et al.
Bioorganic & medicinal chemistry, 15(8), 2963-2974 (2007-02-27)
Norbormide [5-(alpha-hydroxy-alpha-2-pyridylbenzyl)-7-(alpha-2-pyridylbenzylidene)-5-norbornene-2,3-dicarboximide] (NRB, 1), an existing but infrequently used rodenticide, is known to be uniquely toxic to rats but relatively harmless to other rodents and mammals. A series of NRB-related analogues were prepared to investigate the structural features responsible for

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