T3126
D-α-Tocopherol succinate
semisynthetic, 1210 IU/g
Synonym(s):
Vitamin E succinate
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About This Item
Empirical Formula (Hill Notation):
C33H54O5
CAS Number:
Molecular Weight:
530.78
NACRES:
NA.28
PubChem Substance ID:
eCl@ss:
34058016
UNSPSC Code:
12352205
EC Number:
224-403-8
MDL number:
Beilstein/REAXYS Number:
4038233
biological source
semisynthetic
Quality Level
form
powder
specific activity
1210 IU/g
color
white to yellow
storage temp.
room temp
SMILES string
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1
InChI
1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1
InChI key
IELOKBJPULMYRW-NJQVLOCASA-N
General description
α-Tocopherol succinate is a fat soluble vitamin. α-Tocopherol is a form of vitamin E, which can be obtained through dietary sources. RRR-α-tocopherol is a natural form of α-Tocopherol.
Application
D-α-Tocopherol succinate has been used:
- to as a dietary supplement to study its immunomodulatory effects in chicks
- as a dietary supplement in pregnant women to evaluate its effects on arsenic exposure
- as an antioxidant to investigate concurrent pathways of cell death due to acute exercise
Biochem/physiol Actions
Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. α-Tocopherol succinate is used along the α-Tocopherol acetate, α-Tocopherol nicotinate and other esterified forms as a vitamin E supplement with similar but differential activities.
α-Tocopherol is also called as a radical-chain breaker due to its anti-oxidant property.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Product Information Sheet
Tocopherols, tocotrienols and tocomonoenols: Many similar molecules but only one vitamin E
Azzi A
Redox Biology, 101259-101259 (2019)
Myocardial apoptosis and mesenchymal stem cells with acute exercise
Arisi MF, et al.
Physiological Reports, 5(11), e13297-e13297 (2017)
J S Drukteinis et al.
Placenta, 26 Suppl A, S87-S95 (2005-04-20)
Maternal cigarette smoking is known to disrupt placental growth and function. The polyaromatic hydrocarbon benzo[a]pyrene (BaP) is a major toxicant in cigarette smoke that has been shown to alter placental cell function. This study compared the effects of the benzo[a]pyrene