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About This Item
Linear Formula:
H2NC6H4OH
CAS Number:
Molecular Weight:
109.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
385836
grade
pharmaceutical primary standard
API family
paracetamol, acetaminophen, mesalazine
manufacturer/tradename
USP
mp
185-189 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
Nc1ccc(O)cc1
InChI
1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
InChI key
PLIKAWJENQZMHA-UHFFFAOYSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.4-Aminophenol is the principal degradation product of acetaminophen, formed as an impurity during its hydrolysis.
For further information and support please go to the website of the issuing Pharmacopoeia.4-Aminophenol is the principal degradation product of acetaminophen, formed as an impurity during its hydrolysis.
Application
This USP reference standard is intended for use in specified quality tests and assays.
Also used to prepare standard and system suitability solutions to test for the presence of 4-aminophenol as an impurity in various pharmaceutical dosage forms of acetaminophen, according to the United States Pharmacopeia (USP) monographs:
Also used to prepare standard and system suitability solutions to test for the presence of 4-aminophenol as an impurity in various pharmaceutical dosage forms of acetaminophen, according to the United States Pharmacopeia (USP) monographs:
- Mesalamine
- Acetaminophen Tablets
- Acetaminophen Oral Suspension
- Tramadol Hydrochloride and Acetaminophen Tablets
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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signalword
Warning
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2
target_organs
Kidney
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
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Tramadol Hydrochloride and Acetaminophen Tablets
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(1), 4450-4450 (2017)
Mesalamine
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(6), 2800-2800 (2020)
Acetaminophen Oral Suspension
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(6), 42-42 (2021)


