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Merck

1099008

USP

Cephalexin

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Cephalexin monohydrate

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About This Item

Empirical Formula (Hill Notation):
C16H17N3O4S · H2O
CAS Number:
23325-78-2
Molecular Weight:
365.40
MDL number:
MFCD00167148
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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Product Name

Cephalexin, United States Pharmacopeia (USP) Reference Standard

SMILES string

S1[C@H]2N(C(=C(C1)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.O

InChI

1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15-;/m1./s1

InChI key

AVGYWQBCYZHHPN-CYJZLJNKSA-N

grade

pharmaceutical primary standard

API family

cephalexin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Cephalexin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Cephalexin Hydrochloride
  • Cephalexin Tablets
  • Cephalexin Capsules
  • Cephalexin for Oral Suspension
  • Cephalexin Tablets for Oral Suspension

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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R S Griffith
Postgraduate medical journal, 59 Suppl 5, 16-27 (1983-01-01)
Cephalexin has an antimicrobial spectrum that includes those pathogens most frequently encountered in clinical practice. It is useful in the treatment of infections of the upper and lower respiratory tract, skin and soft tissue, and the genitourinary tract. It can
M J Raff
Postgraduate medical journal, 59 Suppl 5, 32-39 (1983-01-01)
Cephalexin has had 12 years of extensive clinical usage in the management of respiratory tract and other infections. It is reliably absorbed from the gastrointestinal tract and reaches therapeutic levels in serum and tissues. Toxicity and adverse side effects are
K M Murray et al.
The Annals of pharmacotherapy, 26(10), 1230-1233 (1992-10-01)
To report a case of cephalexin-induced Stevens-Johnson syndrome (SJS), a devastating adverse drug reaction that involves the entire skin surface and mucosal areas of the body. MEDLINE search (key terms cephalosporins, Stevens-Johnson syndrome, erythema multiforme, and systemic lupus erythematosus) and
G L McCloskey et al.
Cutis, 59(5), 251-254 (1997-05-01)
The ampicillin rash occurring in cases of infectious mononucleosis is well documented. Similar phenomena have also been observed with other antibiotics. The case of a patient with infectious mononucleosis treated with cephalexin who later showed a rash is presented and
C W Derrick et al.
Postgraduate medical journal, 59 Suppl 5, 43-46 (1983-01-01)
Cephalexin remains an effective and highly useful antibiotic for the treatment of streptococcal and staphylococcal skin infections. Twelve years of experience have not diminished its efficacy, and cure rates of 90% or higher continue to be achieved. Its resistance to
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