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1375502

USP

Mebendazole

Name: Mebendazole
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, Mebendazol, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₃N₃O₃

CAS Number:

31431-39-7

Molecular Weight:

295.29

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750328

MDL number:

MFCD00057872

Beilstein/REAXYS Number:

759809

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Properties

grade

pharmaceutical primary standard

API family

mebendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mebendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Mebendazole Tablets
Mebendazole Oral Suspension
Fenbendazole
Pimozide Tablets
Pimozide

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

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Certificates of Analysis (COA)

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[Experimental therapy in Chinese hamsters and rats infected with larval Echinococcus multilocularis by using mebendazole, albendazole and ivermectin with brief review of chemotherapy of human multilocular echinococcosis].

T Inaoka et al.

[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 62(1), 54-67 (1987-01-01)

The effects of the mebendazole, albendazole and ivermectin on secondary multilocular echinococcosis in Chinese hamsters infected with intraperitoneal inoculation of protoscolices and in rats infected with transportal inoculation of protoscolices were investigated. A reduction in weight of the hydatids greater

Soil-transmitted helminths in southern highland Rwanda: associated factors and effectiveness of school-based preventive chemotherapy.

Olga Staudacher et al.

Tropical medicine & international health : TM & IH, 19(7), 812-824 (2014-04-23)

Preventive chemotherapy of schoolchildren against soil-transmitted helminths (STHs) is widely implemented in Rwanda. However, data on its actual efficacy are lacking. We assessed prevalence, associated factors and manifestation of STH infection among schoolchildren in southern highland Rwanda as well as

Mebendazole and related anthelmintics.

H Van den Bossche et al.

Advances in pharmacology and chemotherapy, 19, 67-128 (1982-01-01)

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