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05-23-0751

α-Melanocyte-Stimulating Hormone

Name: α-Melanocyte-Stimulating Hormone
Brand: MM

Synthetic α-melanocyte-stimulating hormone.

Synonym(s):

α-Melanocyte-Stimulating Hormone, α-MSH, Melanotropin

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About This Item

Empirical Formula (Hill Notation):

C₇₇H₁₀₉N₂₁O₁₉S

CAS Number:

581-05-5

Molecular Weight:

1664.88

UNSPSC Code:

12352202

NACRES:

NA.77

MDL number:

MFCD00133062

Assay:

≥95% (HPLC)

Form:

lyophilized

Quality level:

100

Storage condition:

OK to freeze

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Properties

Quality Level

100

sterility

non-sterile

assay

≥95% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

S(CC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CO)Cc6ccc(cc6)O)CO)C(=O)N[C@@H](CCC(=O)O)C(=O)NC(Cc5[nH]cnc5)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2c3c([nH]c2)cccc3)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]

InChI

1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58?,59-,60-,61-,64-/m0/s1

InChI key

WHNFPRLDDSXQCL-PDEGJNOBSA-N

Description

General description

Synthetic α-melanocyte-stimulating hormone. Peptide hormone secreted by the anterior pituitary gland. Controls the intensity of pigmentation. A potent inhibitor of ICAM-1 expression in malignant melanocytes.

Packaging

Yes

Physical form

Supplied as trifluoroacetate salt. Sold on the basis of peptide content.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Other Notes

Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂

Morandini, R., et al. 1998. J. Cell Physiol. 175, 276.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c