226084
(Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate
97%, for peptide synthesis
Synonym(s):
BOP, BOP Reagent, Castros reagent
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About This Item
Empirical Formula (Hill Notation):
C12H22F6N6OP2
CAS Number:
Molecular Weight:
442.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352107
EC Number:
260-279-1
MDL number:
Beilstein/REAXYS Number:
4287025
Product Name
(Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate, 97%
Quality Level
assay
97%
form
powder
reaction suitability
reaction type: Coupling Reactions
mp
>130 °C (dec.) (lit.)
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
SMILES string
F[P-](F)(F)(F)(F)F.CN(C)[P+](On1nnc2ccccc12)(N(C)C)N(C)C
InChI
1S/C12H22N6OP.F6P/c1-15(2)20(16(3)4,17(5)6)19-18-12-10-8-7-9-11(12)13-14-18;1-7(2,3,4,5)6/h7-10H,1-6H3;/q+1;-1
InChI key
MGEVGECQZUIPSV-UHFFFAOYSA-N
Application
Reagent for:
Peptide coupling
Synthesis of esters
Esterification of carboxylic acids
Plasmid CAN-encapsulating liposomes
Synthesis of magnolamide for antioxidative activity
Catalyst for preparation of 9-acridinecaroboxamide derivative
Peptide coupling
Synthesis of esters
Esterification of carboxylic acids
Plasmid CAN-encapsulating liposomes
Synthesis of magnolamide for antioxidative activity
Catalyst for preparation of 9-acridinecaroboxamide derivative
signalword
Danger
hcodes
Hazard Classifications
Flam. Sol. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
supp_hazards
Storage Class
4.1A - Other explosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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W. Chiou, et al.,
Heterocycles, 65, 1215-1220 (2005)
Yosuke Obata et al.
Biochimica et biophysica acta, 1788(5), 1148-1158 (2009-03-03)
We have synthesized a series of cationic amino acid-based lipids having a spacer between the cationic head group and hydrophobic moieties and examined the influence of the spacer on a liposome gene delivery system. As a comparable spacer, a hydrophobic
S100A12 Expression Is Modulated During Monocyte Differentiation and Reflects Periodontitis Severity.
Ronaldo Lira-Junior et al.
Frontiers in immunology, 11, 86-86 (2020-02-23)
S100A12 is a calcium-binding protein of the S100 subfamily of myeloid-related proteins that acts as an alarmin to induce a pro-inflammatory innate immune response. It has been linked to several chronic inflammatory diseases, however its role in the common oral