A1028
8-Anilino-1-naphthalenesulfonic acid
≥97% purity (HPLC), powder
Synonym(s):
N-Phenyl peri acid, ANS, ANSA
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About This Item
Linear Formula:
C6H5NHC10H6SO3H
CAS Number:
Molecular Weight:
299.34
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
1843887
Product Name
8-Anilino-1-naphthalenesulfonic acid,
assay
≥97% (HPLC)
Quality Level
form
powder
composition
, <0.5% (solvent)
color
black, gray to dark green
mp
215-217 °C (dec.) (lit.)
solubility
DMF: 50 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
OS(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12
InChI
1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)
InChI key
FWEOQOXTVHGIFQ-UHFFFAOYSA-N
Application
8-Anilino-1-naphthalenesulfonic acid (ANS) has been used to study the thermal aggregation of BSA (bovine serum albumin).
Biochem/physiol Actions
8-Anilino-1-naphthalenesulfonic acid (ANS) is an important dye which is used to study the intermediate states in the folding/unfolding pathways of proteins. It is also useful to check the conformational changes involved with the aggregation of proteins. ANS is nonfluorescent in the aqueous solution, however, it fluoresces strongly upon binding to BSA (bovine serum albumin) and denatured proteins. It is used for the detection of albumin in the serum. ANS mainly interacts with the solvent exposed nonpolar (hydrophobic) sites.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Uversky VN and Permiakov EA
Methods in Protein Structure and Stability Analysis (2007)
Thermal aggregation of glycated bovine serum albumin.
Rondeau P, et al.
Biochimica et Biophysica Acta, 1804, 789-789 (2010)
Nannan Chen et al.
Journal of agricultural and food chemistry, 62(39), 9553-9561 (2014-09-03)
In this study, we examined the possibility of preparing stable soy protein nanogels by simply heating homogeneous soy protein dispersion. The protein nanogels formed were characterized by z-average hydrodynamic diameter, polydispersity index, turbidity, ζ-potential, morphology, and their stability to pH