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Y0000039

Sodium ascorbate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(+)-Sodium L-ascorbate, L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
134-03-2
Molecular Weight:
198.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329830824
MDL number:
MFCD00082340
Beilstein/REAXYS Number:
3767246

Key Documents

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Product Name

Sodium ascorbate, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

sodium ascorbate

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

220 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Sodium ascorbate may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 1

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Sodium ascorbate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6997-6998 (2019)
, Book author=
Handbook of Pharmaceutical Excipients (2009)
Marina A Kozuleva et al.
FEBS letters, 588(23), 4364-4368 (2014-10-15)
O2 reduction was investigated in photosystem I (PSI) complexes isolated from cyanobacteria Synechocystis sp. PCC 6803 wild type (WT) and menB mutant strain, which is unable to synthesize phylloquinone and contains plastoquinone at the quinone-binding site A1. PSI complexes from
Aleksander Hinek et al.
Journal of dermatological science, 75(3), 173-182 (2014-07-13)
Vitamin C (L-ascorbic acid), a known enhancer of collagen deposition, has also been identified as an inhibitor of elastogenesis. Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic
Curt T Dellavalle et al.
International journal of cancer, 134(12), 2917-2926 (2013-11-19)
Nitrate and nitrite are precursors of endogenously formed N-nitroso compounds (NOC), known animal carcinogens. Nitrosation reactions forming NOCs can be inhibited by vitamin C and other antioxidants. We prospectively investigated the association between dietary nitrate and nitrite intake and risk
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