104R-1
CD4 (SP35) Rabbit Monoclonal Antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
SP35, monoclonal
Application:
IHC (p)
Citations:
5
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
SP35, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (104R-14), vial of 0.5 mL concentrate (104R-15), bottle of 1.0 mL predilute (104R-17), vial of 1.0 mL concentrate (104R-16), bottle of 7.0 mL predilute (104R-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic, membranous
Gene Information
human ... CD4(920)
General description
CD4 is a 55-kD glycoprotein expressed on the surface of T-helper/regulatory T-cells,monocytes, macrophages, and some dendritic cells. The majority of peripheral T-celllymphomas are derived from the T-helper/regulatory cell subset so most matureT-cell neoplasms are CD4+. Anti-CD4 is used to identify normal T-cells and to aid in theidentification of neoplasms of T-cell origin.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD4 Positive Control Slides, Product No. 104S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Manual of Diagnostic Antibodies for Immunohistology (2003)
Cynthia Lehe et al.
Cancer research, 68(15), 6350-6359 (2008-08-05)
Compelling evidences indicate a key role for regulatory T cells (T(reg)) on the host response to cancer. The Wilms' tumor antigen (WT1) is overexpressed in several human leukemias and thus considered as promising target for development of leukemia vaccine. However
Takashi Akiyama et al.
Pathology international, 58(10), 626-634 (2008-09-20)
The present study reports five CD8+, CD56+ (natural killer (NK)-like) T-cell lymphomas involving the small intestine without evidence of enteropathy, from Japan. Three were intestinal T-cell lymphoma. The site of origin of the other two was not definitive. Four of