P6744
Picric acid solution
1.3% in H2O (saturated)
Synonym(s):
2,4,6-Trinitrophenol
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About This Item
Linear Formula:
(O2N)3C6H2OH
CAS Number:
Molecular Weight:
229.10
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
423400
Concentration:
1.3% in H2O (saturated)
Form:
liquid
form
liquid
Quality Segment
concentration
1.3% in H2O (saturated)
color
yellow to very dark yellow
density
1.080 g/cm3
application(s)
hematology
histology
storage temp.
room temp
SMILES string
Oc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O
InChI
1S/C6H3N3O7/c10-6-4(8(13)14)1-3(7(11)12)2-5(6)9(15)16/h1-2,10H
InChI key
OXNIZHLAWKMVMX-UHFFFAOYSA-N
General description
Picric acid is a polynitrated aromatic acid. It dissolves in water to form a solution with low pH (pH 2.0). It interacts with basic groups of proteins, forms salts and coagulates them. Fixation with picric acid gives a bright stain, but there might be a loss of nucleic acids due to the low pH of the solution.
Picric acid is anionic and has a low molecular weight.
Picric acid is anionic and has a low molecular weight.
Application
Picric acid is commonly used as a fixative and staining reagent in forensic and histological applications. It is a general cytoplasmic stain, connective tissue fiber stain, and a fixative for tissues.
- It is a component of picrosirius red which is used to stain collagen.
- Bouin’s fluid which also comprises picric acid is a fixative for nuclei and connective tissue.
- It can be used as a colorimetric reagent in creatinine determination assay.
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supp_hazards
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves
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