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SML0224

HI-6

Name: HI-6
Brand: SIGMA

≥98% (HPLC), oxime cholinesterase reactivator, powder

Synonym(s):

1-[[[4-(Aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]-pyridinium chloride, 4-Carbamoyl-1-[[[2-[(hydroxyimino)methyl]pyridinium-1-yl]methoxy]methyl]pyridinium dichloride, Asoxime chloride, HI 6, HI 6 chloride, HJ 6, Transant

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₆N₄O₃ · 2Cl

CAS Number:

34433-31-3

Molecular Weight:

359.21

UNSPSC Code:

12352200

PubChem Substance ID:

329825243

NACRES:

NA.77

MDL number:

MFCD00869535

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Product Name

HI-6, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H₂O: 15 mg/mL (clear solution)

shipped in

wet ice

storage temp.

−20°C

SMILES string

[Cl-].[Cl-].NC(=O)c1cc[n+](COC[n+]2ccccc2\C=N\O)cc1

InChI

1S/C14H14N4O3.2ClH/c15-14(19)12-4-7-17(8-5-12)10-21-11-18-6-2-1-3-13(18)9-16-20;;/h1-9H,10-11H2,(H-,15,19);2*1H

InChI key

QELSIJXWEROXOE-UHFFFAOYSA-N

Description

General description

HI-6 functions as an antidote for treating intoxication caused by nerve agents. It acts as a potent drug in radiation protection and suppresses oxidative stress. HI-6 prevents the toxicity of the antineoplastic drug irinotecan.

Biochem/physiol Actions

HI-6 is an efficient oxime cholinesterase reactivator that is used as an antidote for organophosphates (Ops) exposure.

HI-6 is an efficient oxime cholinesterase reactivator.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c