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Merck

74680

Octaethylene glycol monododecyl ether

BioXtra, ≥98.0% (GC)

Synonym(s):

C12E8, Dodecyl octaethylene glycol ether, Dodecyloctaglycol, Polyoxyethylene (8) lauryl ether

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)8OH
CAS Number:
Molecular Weight:
538.75
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1893466
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description

non-ionic

Quality Level

product line

BioXtra

assay

≥98.0% (GC)

form

solid

mol wt

538.75 g/mol

CMC

0.11

cation traces

Ca: ≤50 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cr: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, K: ≤50 mg/kg, Mg: ≤50 mg/kg, Mn: ≤50 mg/kg, Na: ≤50 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3

InChI key

YYELLDKEOUKVIQ-UHFFFAOYSA-N

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General description

Octaethylene glycol monododecyl ether is a nonionic detergent.

Application

Detergent used for the study of membrane proteins in a native-like state, e.g. ATPase. Used in a mixed micellar assay for lipoxygenase acting at neutral pH and for functional reconstitution of influenza virus envelopes.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Leopold Kremser et al.
Electrophoresis, 27(13), 2630-2637 (2006-05-30)
Human rhinoviruses (HRVs), the main etiologic agents of the common cold, transform into subviral B- or 80S particles (they sediment at 80S upon sucrose density gradient centrifugation) during infection and, in vitro, upon exposure to a temperature between 50 and
G C Troiano et al.
Biophysical journal, 75(2), 880-888 (1998-07-24)
The effects of a nonionic surfactant, octaethyleneglycol mono n-dodecyl ether (C12E8), on the electroporation of planar bilayer lipid membranes made of the synthetic lipid 1-pamitoyl 2-oleoyl phosphatidylcholine (POPC), was studied. High-amplitude ( approximately 100-450 mV) rectangular voltage pulses were used
Leandro Ramos Souza Barbosa et al.
The journal of physical chemistry. B, 114(35), 11371-11376 (2010-08-19)
In the current work, we studied the effect of the nonionic detergent dodecyloctaethyleneglycol, C(12)E(8), on the structure and oligomeric form of the Na,K-ATPase membrane enzyme (sodium-potassium pump) in aqueous suspension, by means of small-angle X-ray scattering (SAXS). Samples composed of
Hiren Patel et al.
Biophysical chemistry, 150(1-3), 119-128 (2010-04-27)
We have studied the effect of two cosolvents, urea and glycerol, on the association and interactions of a surfactant, octaethyleneglycol dodecyl ether (C(12)EO(8)) and a phospholipid (POPC). We have measured the CMC, the partition coefficient, the effective mole fractions X(e)(sat)
M R Wenk et al.
Biophysical journal, 72(4), 1719-1731 (1997-04-01)
The interaction of the nonionic detergent octyl-beta-D-glucopyranoside (OG) with lipid bilayers was studied with high-sensitivity isothermal titration calorimetry (ITC) and solid-state 2H-NMR spectroscopy. The transfer of OG from the aqueous phase to lipid bilayers composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) can be

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