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Merck

901219

VPhos Pd G3

95%, powder or crystals

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About This Item

Empirical Formula (Hill Notation):
C46H62NO4PPdS
Molecular Weight:
862.45
UNSPSC Code:
12161600
NACRES:
NA.22
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Product Name

VPhos Pd G3, 95%

Quality Level

product line

Buchwald precatalyst Generation 3

assay

95%

form

powder or crystals

feature

generation 3

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
reaction type: Cross Couplings

functional group

phosphine

Application

Buchwald palladacycle precatalyst with new biaryl(dialkyl)phosphine ligand, VPhos, has an improved activity profile for the reductive coupling of non-aromatic heterocyclic alkyl bromides. Its combined use with a surfactant system of octanoic acid/sodium octanoate enables Negishi coupling and access to diverse C(sp3)–C(sp2) cross-coupled products.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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