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About This Item
Linear Formula:
C6H3FN2O4S · NH3
CAS Number:
Molecular Weight:
235.19
UNSPSC Code:
23151817
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5199564
Assay:
≥98.5% (HPLC)
grade
derivatization grade (HPLC)
Quality Level
assay
≥98.5% (HPLC)
quality
LiChropur™
technique(s)
HPLC: suitable
fluorescence
λex 385 nm; λem 524 nm in 0.1 M borate pH 9.5 (after derivatization with glutathione)
storage temp.
2-8°C
SMILES string
N.OS(=O)(=O)c1ccc(F)c2nonc12
InChI
1S/C6H3FN2O4S.H3N/c7-3-1-2-4(14(10,11)12)6-5(3)8-13-9-6;/h1-2H,(H,10,11,12);1H3
InChI key
JXLHNMVSKXFWAO-UHFFFAOYSA-N
Application
Fluorescent probe for thiols and pre-column labeling of biological thiols for HPLC
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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K Noguchi et al.
Journal of pharmaceutical and biomedical analysis, 10(7), 515-520 (1992-07-01)
A HPLC method is developed for the determination of glutathione isopropyl ester, a drug for the treatment of cerebral vascular disease, in rat, dog and human blood. The blood is deproteinized with sulphosalicylic acid and the clear supernatant treated with
I Daskalakis et al.
Biomedical chromatography : BMC, 10(5), 205-212 (1996-09-01)
A sensitive HPLC-fluorescence method for determining total endogenous plasma homocysteine (Hcy), cysteine (Cys) and cysteinylglycine (Cys-Gly) following derivatization with ammonium 7-fluoro 2,1,3-benzoxadiazole-4-sulphonate (SBD-F) is described. Quantitation utilizes an internal standard, 2-mercaptoethylamine. The derivatization procedure has been optimized for concentration of
Total plasma homocysteine analysis by HPLC with SBD-F precolumn derivatization.
I Fermo et al.
Methods in molecular biology (Clifton, N.J.), 159, 237-244 (2000-10-29)