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About This Item
Empirical Formula (Hill Notation):
C5H12N2O2 · 2HCl
CAS Number:
Molecular Weight:
205.08
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
228-277-5
Beilstein/REAXYS Number:
4538819
MDL number:
assay
≥99.0% (AT)
form
crystals
optical activity
[α]20/D +17±1°, c = 5% in H2O
technique(s)
ligand binding assay: suitable
ign. residue
≤0.1% (as SO4)
color
colorless
mp
197-199 °C (dec.)
anion traces
sulfate (SO42-): ≤100 mg/kg
cation traces
As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, NH4+: ≤100 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
SMILES string
Cl.Cl.NCCC[C@H](N)C(O)=O
InChI
1S/C5H12N2O2.2ClH/c6-3-1-2-4(7)5(8)9;;/h4H,1-3,6-7H2,(H,8,9);2*1H/t4-;;/m0../s1
InChI key
HGBAVEGDXFHRQP-FHNDMYTFSA-N
Biochem/physiol Actions
L-Ornithine is a non-proteinogenic recycled component of the Urea Cycle leading to the production of arginine. L-ornithine is the starting compound for polyamine biosynthesis via ornithine decarboxylase.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Francois Blachier et al.
Frontiers in bioscience (Landmark edition), 16, 1331-1343 (2011-01-05)
Colon epithelium is renewed within few days through asymmetric mitosis of pluripotent cells followed by differentiation and exfoliation. Absorptive colonocytes do not transport amino acids from lumen to bloodstream but import amino acids from plasma. Among amino acids, colonocytes can
V Walker
Diabetes, obesity & metabolism, 11(9), 823-835 (2009-06-18)
The urea cycle is the final pathway for removal of surplus nitrogen from the body, and the major route in humans for detoxification of ammonia. The full complement of enzymes is expressed only in liver. Inherited deficiencies of urea cycle
Markus Munder
British journal of pharmacology, 158(3), 638-651 (2009-09-22)
The enzyme arginase metabolizes L-arginine to L-ornithine and urea. Besides its fundamental role in the hepatic urea cycle, arginase is also expressed the immune system of mice and man. While significant interspecies differences exist regarding expression, subcellular localization and regulation