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Merck

M5760

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan

>97.5% purity (HPLC), powder

Synonym(s):

4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole, MBD

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About This Item

Empirical Formula (Hill Notation):
C14H12N4O4
CAS Number:
33984-50-8
Molecular Weight:
300.27
NACRES:
NA.47
PubChem Substance ID:
24897041
UNSPSC Code:
12171500
EC Number:
251-775-9
MDL number:
MFCD00042778
Beilstein/REAXYS Number:
1151390

Key Documents

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Product Name

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan,

InChI key

IENONFJSMWUIQQ-UHFFFAOYSA-N

InChI

1S/C14H12N4O4/c1-21-10-4-2-9(3-5-10)8-15-11-6-7-12(18(19)20)14-13(11)16-22-17-14/h2-7,15H,8H2,1H3

SMILES string

COc1ccc(CNc2ccc([N+]([O-])=O)c3nonc23)cc1

assay

>97.5% (HPLC)

form

powder

color

orange to red

solubility

DMSO:methanol (1:1): 50 mg/mL, clear, orange

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

Quality Level

100

Related Categories

Application

Fluorescent probe for hydrophobic (non-polar) regions in proteins and nucleoproteins.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKBR6862V
MKBR8092V
051M1274V
051M1273V
SLBG6369V

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Ke Liu et al.
The FEBS journal, 286(16), 3240-3254 (2019-04-14)
The MBD3, a methyl-CpG-binding domain (MBD)-containing protein, is a core subunit of the Mi-2/NuRD complex. Recent reports show that MBD3 recognizes both methylated CG (mCG)- and hydroxymethylated CG (hmCG)-containing DNA, with a preference for hmCG. However, whether the MBD3-MBD indeed
Sevda Tanrıkulu-Küçük et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 44(7), 774-782 (2019-01-04)
This study investigated the effects of curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet (HFD). Male Sprague-Dawley rats were divided into 5 groups (8 rats per group). The control group was fed a
Michelle Lowe et al.
Frontiers in microbiology, 9, 1280-1280 (2018-06-28)
Acinetobacter baumannii is an opportunistic pathogen that is increasingly responsible for hospital-acquired infections. The increasing prevalence of carbapenem resistant A. baumannii has left clinicians with limited treatment options. Last line antimicrobials (i.e., polymyxins and glycylcyclines) are often used as treatment
Shingo Fukuma et al.
Scientific reports, 9(1), 11301-11301 (2019-08-07)
Achieving calcium, phosphorus, and intact parathyroid hormone (PTH) targets helps improve dialysis population outcomes. We aimed to assess the population-level associations of achievement of those targets with survival using population-attributable-fractions (PAFs). We conducted a case-cohort study using data from 8229
Angharad R Morgan et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 15(6), 776-787 (2019-05-03)
Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. A hypothesis-led plasma biomarker search was conducted in the context of international multicenter studies. The discovery
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