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114715

Phenylhydrazine hydrochloride

≥99%

Synonym(s):

Phenylhydrazinium chloride

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About This Item

Linear Formula:
C6H5NHNH2 · HCl
CAS Number:
59-88-1
Molecular Weight:
144.60
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24847191
EC Number:
200-444-7
Beilstein/REAXYS Number:
3594958
MDL number:
MFCD00012924
Assay:
≥99%
Form:
solid
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Quality Segment

200

assay

≥99%

form

solid

mp

250-254 °C (dec.) (lit.)

functional group

hydrazine

SMILES string

Cl[H].NNc1ccccc1

InChI

1S/C6H8N2.ClH/c7-8-6-4-2-1-3-5-6;/h1-5,8H,7H2;1H

InChI key

JOVOSQBPPZZESK-UHFFFAOYSA-N

Application

Phenylhydrazine hydrochloride is used in the examination of tyrosine phosphorylation of Janus protein tyrosine kinase (JAKs) in the EPO-responsive normal erythroblastoid cells of anemic mice.

Biochem/physiol Actions

Phenylhydrazine hydrochloride causes acute hemolysis when injected intraperitoneally in to wild-type and Hp and Hx single-null mice. It suppresses the horseradish peroxide (HRP) residual activity in tissue sections of animals.

Preparation Note

50 gm of Phenylhydrazine hydrochloride dissolves in 1 mL of water to yield a clear, very faint yellow solution.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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