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Merck

137448

2-Methyl-2-oxazoline

98%

Synonym(s):

2-Methyloxazoline

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About This Item

Empirical Formula (Hill Notation):
C4H7NO
CAS Number:
Molecular Weight:
85.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
214-316-3
Beilstein/REAXYS Number:
104227
MDL number:
Assay:
98%
Form:
liquid
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InChI key

GUXJXWKCUUWCLX-UHFFFAOYSA-N

InChI

1S/C4H7NO/c1-4-5-2-3-6-4/h2-3H2,1H3

SMILES string

CC1=NCCO1

assay

98%

form

liquid

Quality Level

bp

109.5-110.5 °C (lit.)

density

1.005 g/mL at 25 °C (lit.)

General description

2-Methyl-2-oxazoline undergoes polymerization with 2-butyl-2-oxazoline to form poly(2-oxazoline) block copolymer. It undergoes cationic ring-opening polymerization with 2-(dec-9-enyl)-2-oxazoline to yield copoly(2-oxazoline)s.

Application

2-Methyl-2-oxazoline was used in cationic polymerization of a series of linear 2-alkyl-2-oxazolines under microwave irradiation.

pictograms

Flame

signalword

Danger

hcodes

pcodes

Hazard Classifications

Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

68.0 °F - closed cup

flash_point_c

20 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Yalin Zhang et al.
Talanta, 150, 375-387 (2016-02-04)
Nitrogen-rich melamine (66% by mass) had been found to be illegally adulterated to milk products and animal feed in order to increase the apparent protein content, and ingestion of melamine may lead to the formation of kidney stones. Hence, the
Pavel Sťahel et al.
Polymers, 11(12) (2019-12-18)
Polyoxazolines are a new promising class of polymers for biomedical applications. Antibiofouling polyoxazoline coatings can suppress bacterial colonization of medical devices, which can cause infections to patients. However, the creation of oxazoline-based films using conventional methods is difficult. This study
Jing Tong et al.
Molecular pharmaceutics, 10(1), 360-377 (2012-11-21)
Superoxide dismutase 1 (SOD1) efficiently catalyzes dismutation of superoxide, but its poor delivery to the target sites in the body, such as brain, hinders its use as a therapeutic agent for superoxide-associated disorders. Here to enhance the delivery of SOD1
Ke Mao et al.
Talanta, 168, 230-239 (2017-04-11)
In this work, a one-step coating procedure by a simple annealing protocol of poly (2-methyl-2-oxazoline)-random-glycidyl methacrylate (PMOXA-r-GMA) copolymer was used to yield covalent and cross-linked PMOXA-based antifouling coating on a fused-silica capillary inner surface, which was used to determine the
Laetitia Korchia et al.
Soft matter, 13(25), 4507-4519 (2017-06-07)
A series of amphiphilic photo-responsive heterografted copolymers have been successfully synthesized. The random copolymers were composed of a methacrylate backbone, with various compositions of hydrophilic oligomeric 2-methyl-2-oxazoline side chains (OMOx) and hydrophobic long alkyl chains terminated by a coumarin moiety

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